Compile Data Set for Download or QSAR
Report error Found 92 Enz. Inhib. hit(s) with all data for entry = 50031084
TargetHepatocyte growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306684(2-(6-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of recombinant c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306677((R)-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306677((R)-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306680(rac-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHepatocyte growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306679(rac-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306685(rac-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 94nMAssay Description:Inhibition of recombinant c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306683((R)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306678(rac-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 205nMAssay Description:Inhibition of recombinant c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306684(2-(6-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant RON by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306686(rac-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 368nMAssay Description:Inhibition of recombinant c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306684(2-(6-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 430nMAssay Description:Inhibition of recombinant AXL by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306677((R)-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 450nMAssay Description:Inhibition of recombinant RON by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306681((S)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Affinity DataIC50: 453nMAssay Description:Inhibition of recombinant c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306677((R)-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 570nMAssay Description:Inhibition of recombinant AXL by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306681((S)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306683((R)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of recombinant RON by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306677((R)-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of recombinant EphA2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306684(2-(6-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of recombinant EphA2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306677((R)-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of recombinant Aurora A by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306677((R)-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of recombinant FGFR2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetLeukocyte tyrosine kinase receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306684(2-(6-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant LTK by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant KDR by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306677((R)-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant Abl by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306677((R)-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant KDR by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306684(2-(6-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant FGFR2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306677((R)-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant LCK by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306683((R)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant AXL by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306684(2-(6-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant Flt3 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetLeukocyte tyrosine kinase receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306677((R)-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant LTK by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306681((S)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant Src by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306684(2-(6-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of recombinant Aurora A by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306683((R)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of recombinant Src by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306683((R)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of recombinant KDR by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306683((R)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of recombinant FGFR2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306684(2-(6-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of recombinant Fyn by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306677((R)-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant YES by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306677((R)-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant KDR by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306684(2-(6-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of recombinant IGF1R by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306684(2-(6-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of recombinant LCK by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306677((R)-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of recombinant Fyn by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306681((S)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant KDR by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306677((R)-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant Flt3 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 6(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306677((R)-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant BRK by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306686(rac-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of recombinant KDR by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306684(2-(6-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of recombinant Kit by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306683((R)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of recombinant Kit by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306686(rac-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of recombinant Src by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306683((R)-6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quino...)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of recombinant Flt3 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306677((R)-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)qu...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant Src by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
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