Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50031490
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314078((5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-23-[...)
Affinity DataKd:  43nMpH: 6.0Assay Description:Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314083((3S,11S,14S,20S,23R,32S,35S,41aS)-20-((1H-imidazol...)
Affinity DataKd:  930nMpH: 7.4Assay Description:Binding affinity to soluble human FcRn at pH 7.4 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314083((3S,11S,14S,20S,23R,32S,35S,41aS)-20-((1H-imidazol...)
Affinity DataKd:  140nMpH: 6.0Assay Description:Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314107((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-...)
Affinity DataKd:  5.90E+3nMpH: 6.0Assay Description:Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314106((S)-N1-((S)-1-((S)-1-((3R,8R,11S,17S,20S,29S,32S,3...)
Affinity DataKd:  3.70E+4nMpH: 7.4Assay Description:Binding affinity to soluble human FcRn at pH 7.4 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314106((S)-N1-((S)-1-((S)-1-((3R,8R,11S,17S,20S,29S,32S,3...)
Affinity DataKd:  5.30E+3nMpH: 6.0Assay Description:Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314082(CHEMBL1089950)
Affinity DataKd:  1.80E+4nMpH: 7.4Assay Description:Binding affinity to soluble human FcRn at pH 7.4 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314082(CHEMBL1089950)
Affinity DataKd:  2.60E+3nMpH: 6.0Assay Description:Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314081((3R,8R,11S,17S,26S,29S,35aS)-8-((S)-2-((S)-2-aceta...)
Affinity DataKd:  74nMpH: 7.4Assay Description:Binding affinity to soluble human FcRn at pH 7.4 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314081((3R,8R,11S,17S,26S,29S,35aS)-8-((S)-2-((S)-2-aceta...)
Affinity DataKd:  62nMpH: 6.0Assay Description:Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314080((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-...)
Affinity DataKd:  170nMpH: 7.4Assay Description:Binding affinity to soluble human FcRn at pH 7.4 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314078((5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-23-[...)
Affinity DataKd:  260nMpH: 7.4Assay Description:Binding affinity to soluble human FcRn at pH 7.4 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314080((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-...)
Affinity DataKd:  31nMpH: 6.0Assay Description:Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314079((5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-23-[...)
Affinity DataKd:  150nMpH: 6.0Assay Description:Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314079((5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-23-[...)
Affinity DataKd:  950nMpH: 7.4Assay Description:Binding affinity to soluble human FcRn at pH 7.4 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314095(CHEMBL1090633)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314105(N1,N4-bis((S)-1-((S)-1-((3R,8R,11S,17S,20S,29S,32S...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314094(CHEMBL1090632)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314093(CHEMBL1090631)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314102(CHEMBL1090640)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314090(N-[(1S)-1-{[(1S)-1-{[(5S,8S,15S,18R,23R,26S,32S,35...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314103((R,S,S,3R,3'R,8R,8'R,11S,11'S,17S,17'S,20S,20'S,29...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314100((S)-N1,N4-bis((S)-1-((S)-1-((3R,8R,11S,17S,20S,29S...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314098(CHEMBL1090636)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314096(CHEMBL1090634)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314099(N1,N5-bis((S)-1-((S)-1-((3R,8R,11S,17S,20S,29S,32S...)
Affinity DataIC50: 5nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314097(N1,N1'-(ethane-1,2-diyl)bis(N4-((S)-1-((S)-1-((3R,...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314101((S)-N1,N5-bis((S)-1-((S)-1-((3R,8R,11S,17S,20S,29S...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314091(N-[(1S)-1-{[(1S)-1-{[(5S,8S,15S,18R,23R,26S,32S,35...)
Affinity DataIC50: 18nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314104(N1,N4-bis((S)-1-((S)-1-((3R,8R,11S,17S,26S,29S,35a...)
Affinity DataIC50: 20nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314092(CHEMBL1090280)
Affinity DataIC50: 50nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314078((5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-23-[...)
Affinity DataIC50: 430nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314080((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-...)
Affinity DataIC50: 520nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314088(CHEMBL1090276)
Affinity DataIC50: 580nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314084(CHEMBL1089952)
Affinity DataIC50: 600nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314087(CHEMBL1090275)
Affinity DataIC50: 710nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314081((3R,8R,11S,17S,26S,29S,35aS)-8-((S)-2-((S)-2-aceta...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314086(CHEMBL1090274)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314079((5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-23-[...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314083((3S,11S,14S,20S,23R,32S,35S,41aS)-20-((1H-imidazol...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314085(CHEMBL1090273)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314089(CHEMBL1090277)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314082(CHEMBL1089950)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314107((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetIgG receptor FcRn large subunit p51(Human)
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314106((S)-N1-((S)-1-((S)-1-((3R,8R,11S,17S,20S,29S,32S,3...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed