Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50031280
TargetMAP kinase-activated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310343(6-{3-amino-1-[3-(1H-indol-6-yl)phenyl]-1H-pyrazol-...)
Affinity DataIC50: 61nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMAP kinase-activated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310342(6-(1-(3-(1H-benzo[d]imidazol-6-yl)phenyl)-3-amino-...)
Affinity DataIC50: 82nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310352(7-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)-3,...)
Affinity DataIC50: 84nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310356(6-(3-amino-1-(3'-methoxybiphenyl-3-yl)-1H-pyrazol-...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310341(N-(3'-(3-amino-4-(1-oxo-1,2,3,4-tetrahydroisoquino...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310355(6-(3-amino-1-(3'-hydroxybiphenyl-3-yl)-1H-pyrazol-...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310345(6-(3-amino-1-(3-(2-oxoindolin-6-yl)phenyl)-1H-pyra...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310344(6-(3-amino-1-(3-(1-methyl-1H-indol-6-yl)phenyl)-1H...)
Affinity DataIC50: 290nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310354(7-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)-3,...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM30311(Pyrrolo-pyrimidone, 4)
Affinity DataIC50: 540nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310353(8-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)-2,...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310347(4-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)ben...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310351(5-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)iso...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310343(6-{3-amino-1-[3-(1H-indol-6-yl)phenyl]-1H-pyrazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310343(6-{3-amino-1-[3-(1H-indol-6-yl)phenyl]-1H-pyrazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310343(6-{3-amino-1-[3-(1H-indol-6-yl)phenyl]-1H-pyrazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310343(6-{3-amino-1-[3-(1H-indol-6-yl)phenyl]-1H-pyrazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310350(4-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)ben...)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310348(4-(5-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)ben...)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310346(4-(1-(4-methoxyphenyl)-1H-pyrazol-4-yl)benzamide |...)
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50310349(4-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)ben...)
Affinity DataIC50: 3.12E+4nMAssay Description:Inhibition of human MK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed