Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50031260
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50310078((R/S)-1-(3-(6-Methoxynaphthalen-2-yl)butyl)piperid...)
Affinity DataKi:  1.29nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat liver homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50310077((R/S)-N-Benzyl-3-(6-methoxynaphthalen-2-yl)-N-meth...)
Affinity DataKi:  2.31nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat liver homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50310074((R/S)-4-(benzyl(methyl)amino)-2-(biphenyl-4-yl)but...)
Affinity DataKi:  2.38nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat liver homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50198062((R/S)-N-Benzyl-3-(biphenyl-4-yl)-N-methylbutan-1-a...)
Affinity DataKi:  3.59nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat liver homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50198065(CHEMBL1917697 | CHEMBL224099 | 4(E)-N-Benzyl-3-(bi...)
Affinity DataKi:  4.17nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat liver homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50310076((E)-1-(3-(6-Methoxynaphthalen-2-yl)but-2-enyl)pipe...)
Affinity DataKi:  4.41nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat liver homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50310072((R/S)-4-(Benzyl(methyl)amino)-2-(6-methoxynaphthal...)
Affinity DataKi:  6.04nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat liver homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50310073((R/S)-2-(6-Methoxynaphthalen-2-yl)-4-(piperidin-1-...)
Affinity DataKi:  10.4nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat liver homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50310075((E)-N-Benzyl-3-(6-methoxynaphthalen-2-yl)-N-methyl...)
Affinity DataKi:  13.7nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat liver homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50198055((R/S)-N,N-dimethyl-3-(6-methoxy-naphthalen-2-yl) b...)
Affinity DataKi:  14.4nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat liver homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50198066((E)-N,N-dimethyl-3-(6-methoxy-naphthalen-2-yl)but-...)
Affinity DataKi:  27.3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat liver homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50310071((R/S)-4-(Dimethylamino)-2-(6-methoxynaphthalen-2-y...)
Affinity DataKi:  38.8nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat liver homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50310072((R/S)-4-(Benzyl(methyl)amino)-2-(6-methoxynaphthal...)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50310077((R/S)-N-Benzyl-3-(6-methoxynaphthalen-2-yl)-N-meth...)
Affinity DataKi:  171nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50198062((R/S)-N-Benzyl-3-(biphenyl-4-yl)-N-methylbutan-1-a...)
Affinity DataKi:  248nMAssay Description:Displacement of [3H]DAMGO from mu-type opioid receptor in guinea pig brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50310077((R/S)-N-Benzyl-3-(6-methoxynaphthalen-2-yl)-N-meth...)
Affinity DataKi:  841nMAssay Description:Displacement of [3H]-U-69593 from kappa-type opioid receptor in guinea pig brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed