Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 8084
TargetCarboxylic ester hydrolase(Horse)
Chung Shan Medical University Hospital

LigandPNGBDBM232997((S)-(-)-endo-2-norbornyl-N-n-butylcarbamate)
Affinity DataKi:  2nM ΔG°:  -49.7kJ/molepH: 7.0 T: 2°CAssay Description:BChE inhibitions by the carbamate inhibitors were assayed by the Ellman method [Ellman et al., Biochem. Pharm., 7:88-95]. BChE-catalyzed hydrolysis o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Chung Shan Medical University Hospital

LigandPNGBDBM232998(rac-(-)-endo-2-norbornyl carbamate | (R)-(+)-endo-...)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/molepH: 7.0 T: 2°CAssay Description:BChE inhibitions by the carbamate inhibitors were assayed by the Ellman method [Ellman et al., Biochem. Pharm., 7:88-95]. BChE-catalyzed hydrolysis o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Chung Shan Medical University Hospital

LigandPNGBDBM232998(rac-(-)-endo-2-norbornyl carbamate | (R)-(+)-endo-...)
Affinity DataKi:  5nM ΔG°:  -47.4kJ/molepH: 7.0 T: 2°CAssay Description:BChE inhibitions by the carbamate inhibitors were assayed by the Ellman method [Ellman et al., Biochem. Pharm., 7:88-95]. BChE-catalyzed hydrolysis o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Chung Shan Medical University Hospital

LigandPNGBDBM232995((R)-(+)-exo-2-norbonyl-N-n-butylcarbamate)
Affinity DataKi:  11nM ΔG°:  -45.4kJ/molepH: 7.0 T: 2°CAssay Description:BChE inhibitions by the carbamate inhibitors were assayed by the Ellman method [Ellman et al., Biochem. Pharm., 7:88-95]. BChE-catalyzed hydrolysis o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Chung Shan Medical University Hospital

LigandPNGBDBM232999(rac-(-)-exo-2-norbornyl carbamate)
Affinity DataKi:  30nM ΔG°:  -42.9kJ/molepH: 7.0 T: 2°CAssay Description:BChE inhibitions by the carbamate inhibitors were assayed by the Ellman method [Ellman et al., Biochem. Pharm., 7:88-95]. BChE-catalyzed hydrolysis o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Chung Shan Medical University Hospital

LigandPNGBDBM232996((S)-(-)-exo-2-norbonyl-N-n-butylcarbamate)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.0 T: 2°CAssay Description:BChE inhibitions by the carbamate inhibitors were assayed by the Ellman method [Ellman et al., Biochem. Pharm., 7:88-95]. BChE-catalyzed hydrolysis o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed