Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 50039076
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309191(2-Amino-N-(2-aminoethyl)-5-(2,3-dihydrothieno[3,4-...)
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309182(4-(2-Amino-5-(2,3-dihydrothieno[3,4-b][1,4]dioxin-...)
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of CHK2 in human HT29 cells assessed as blockade of etoposide-induced DNA damage-activated enzyme phosphorylation by Western blotingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309178(4-(2-Amino-5-(benzo[d][1,3]dioxol-4-yl)pyridin-3-y...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of CHK2 in human HT29 cells assessed as blockade of etoposide-induced DNA damage-activated enzyme phosphorylation by Western blotingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309191(2-Amino-N-(2-aminoethyl)-5-(2,3-dihydrothieno[3,4-...)
Affinity DataIC50: 28nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309209(2-Amino-N-(2-aminoethyl)-5-(thiophen-3-yl)nicotina...)
Affinity DataIC50: 39nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309182(4-(2-Amino-5-(2,3-dihydrothieno[3,4-b][1,4]dioxin-...)
Affinity DataIC50: 92nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309178(4-(2-Amino-5-(benzo[d][1,3]dioxol-4-yl)pyridin-3-y...)
Affinity DataIC50: 210nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309194(TCMDC-133349 | 4-(2-Amino-5-(3,4-dimethoxyphenyl)p...)
Affinity DataIC50: 270nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309206(4-(2-Amino-5-(4-hydroxy-3-methoxyphenyl)pyridin-3-...)
Affinity DataIC50: 310nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309184(4-(2-Amino-5-(thiophen-2-yl)pyridin-3-yl)benzamide...)
Affinity DataIC50: 350nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309187(2-Amino-N-(3-amino-3-oxopropyl)-5-(thiophen-3-yl)n...)
Affinity DataIC50: 410nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309186(4-(2-Amino-5-(3-(2-methoxyethoxy)phenyl)pyridin-3-...)
Affinity DataIC50: 420nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309210(4-(2-Amino-5-(3-methoxyphenyl)pyridin-3-yl)benzami...)
Affinity DataIC50: 600nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309211(4-(2-Amino-5-(thiophen-3-yl)pyridin-3-yl)benzamide...)
Affinity DataIC50: 610nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309199(4-(2-Amino-5-(thiazol-5-yl)pyridin-3-yl)benzamide ...)
Affinity DataIC50: 680nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309190(2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-Y...)
Affinity DataIC50: 700nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309209(2-Amino-N-(2-aminoethyl)-5-(thiophen-3-yl)nicotina...)
Affinity DataIC50: 780nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309208(4-(2-Amino-5-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)...)
Affinity DataIC50: 830nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309207(4-(2-Amino-5-(thiazol-2-yl)pyridin-3-yl)benzamide ...)
Affinity DataIC50: 990nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309205(4-(2-Amino-5-(4-(2-methoxyethoxy)phenyl)pyridin-3-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309204(4-(2-Amino-5-(thiazol-4-yl)pyridin-3-yl)benzamide ...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309206(4-(2-Amino-5-(4-hydroxy-3-methoxyphenyl)pyridin-3-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309203(4-(2-Amino-5-(benzo[d][1,3]dioxol-5-yl)pyridin-3-y...)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309202(4-(2-Amino-5-(4-methoxyphenyl)pyridin-3-yl)benzami...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309201(4-(6-Amino-3,4'-bipyridin-5-yl)benzamide | CHEMBL5...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309200(4-(6-amino-6'-(3-(dimethylamino)propoxy)-3,3'-bipy...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309199(4-(2-Amino-5-(thiazol-5-yl)pyridin-3-yl)benzamide ...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309198(4-(2-amino-5-(3-fluorophenyl)pyridin-3-yl)benzamid...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309197(4-(2-Amino-5-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309195(4-(6'-Amino-2,3'-bipyridin-5'-yl)benzamide | CHEMB...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309196(4-(6-Amino-3,3'-bipyridin-5-yl)benzamide | CHEMBL6...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309194(TCMDC-133349 | 4-(2-Amino-5-(3,4-dimethoxyphenyl)p...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309193(4-(2-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309192(4-(5-(3-acetamidophenyl)-2-aminopyridin-3-yl)benza...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309191(2-Amino-N-(2-aminoethyl)-5-(2,3-dihydrothieno[3,4-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309190(2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-Y...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309189(4-(2-amino-5-phenylpyridin-3-yl)benzamide | CHEMBL...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309188(4-(2-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309211(4-(2-Amino-5-(thiophen-3-yl)pyridin-3-yl)benzamide...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309187(2-Amino-N-(3-amino-3-oxopropyl)-5-(thiophen-3-yl)n...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309186(4-(2-Amino-5-(3-(2-methoxyethoxy)phenyl)pyridin-3-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309185(2-Amino-N-(2-(dimethylamino)ethyl)-5-(thiophen-3-y...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309184(4-(2-Amino-5-(thiophen-2-yl)pyridin-3-yl)benzamide...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309183(4-(2-amino-5-(3,5-dimethoxy-4-methylphenyl)pyridin...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309182(4-(2-Amino-5-(2,3-dihydrothieno[3,4-b][1,4]dioxin-...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309181(4-(5-(Thiophen-3-yl)pyridin-3-yl)benzamide | CHEMB...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309180(4-(2-Amino-5-(thiophen-3-yl)pyridin-3-yl)-N,N-dime...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309179(4-(2-Amino-5-(thiophen-3-yl)pyridin-3-yl)-N-methyl...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309178(4-(2-Amino-5-(benzo[d][1,3]dioxol-4-yl)pyridin-3-y...)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
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