Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50031195
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50308764(4-(3,4-Difluorophenyl)-N-(4-methyl-3-(3-methyl-4-o...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50308757(5-(4-Fluorophenyl)-N-(4-methyl-3-(3-methyl-4-oxo-3...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 38nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50308758(5-(3-Chloro-4-fluorophenyl)-N-(4-methyl-3-(3-methy...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50308759(5-(4-Fluoro-3-methylphenyl)-N-(4-methyl-3-(3-methy...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 84nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50308761(N-(4-Methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazoli...)
Affinity DataIC50: 94nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50308765(2-tert-Butyl-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dih...)
Affinity DataIC50: 96nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50308760(5-(3-Fluoro-4-methylphenyl)-N-(4-methyl-3-(3-methy...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50308762(N-(4-Methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazoli...)
Affinity DataIC50: 105nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50308766(N-(4-Methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazoli...)
Affinity DataIC50: 122nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50308755(N-(4-Methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazoli...)
Affinity DataIC50: 405nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50308763(N-(4-Methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazoli...)
Affinity DataIC50: 468nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50308756(N-(4-Methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazoli...)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of human recombinant full length p38alpha assessed as MAPKAPK2 phosphorylation by [32P]ATP SDS-PAGE gel kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed