Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50030690
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM21393(cid_1220 | CHEMBL56 | 7-(dipropylamino)-5,6,7,8-te...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM21395(3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}e...)
Affinity DataKi:  0.850nMAssay Description:Displacement of [3H]ketanserin from 5HT2A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300166(Ethyl 5-(3-(4-(3-chlorophenyl)piperazin-1-yl)propo...)
Affinity DataKi:  1.28nMAssay Description:Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300170(Ethyl 5-(3-(4-(4-chlorophenyl)piperazin-1-yl)propo...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300159(Ethyl 5-(3-(4-((benzo[d][1,3]dioxol-5-yl)methyl)pi...)
Affinity DataKi:  26.1nMAssay Description:Displacement of [3H]ketanserin from 5HT2A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300165(Ethyl 5-(3-(4-(3,4-dichlorophenyl)piperazin-1-yl)p...)
Affinity DataKi:  35.8nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300166(Ethyl 5-(3-(4-(3-chlorophenyl)piperazin-1-yl)propo...)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300162(Ethyl 5-(3-(4-(2-chlorophenyl)piperazin-1-yl)propo...)
Affinity DataKi:  39.7nMAssay Description:Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300159(Ethyl 5-(3-(4-((benzo[d][1,3]dioxol-5-yl)methyl)pi...)
Affinity DataKi:  43.6nMAssay Description:Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300170(Ethyl 5-(3-(4-(4-chlorophenyl)piperazin-1-yl)propo...)
Affinity DataKi:  45.1nMAssay Description:Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300160(Ethyl 5-(3-(4-(4-methoxyphenyl)piperazin-1-yl)prop...)
Affinity DataKi:  50.4nMAssay Description:Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300167(Ethyl 5-(3-(4-(pyridin-2-yl)piperazin-1-yl)propoxy...)
Affinity DataKi:  104nMAssay Description:Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300168(Ethyl 5-(3-(4-(4-nitrophenyl)piperazin-1-yl)propox...)
Affinity DataKi:  247nMAssay Description:Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300169(Ethyl 5-(3-(4-(2-furoyl)piperazin-1-yl)propoxy)-1H...)
Affinity DataKi:  309nMAssay Description:Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300167(Ethyl 5-(3-(4-(pyridin-2-yl)piperazin-1-yl)propoxy...)
Affinity DataKi:  344nMAssay Description:Displacement of [3H]ketanserin from 5HT2A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300169(Ethyl 5-(3-(4-(2-furoyl)piperazin-1-yl)propoxy)-1H...)
Affinity DataKi:  452nMAssay Description:Displacement of [3H]ketanserin from 5HT2A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300162(Ethyl 5-(3-(4-(2-chlorophenyl)piperazin-1-yl)propo...)
Affinity DataKi:  537nMAssay Description:Displacement of [3H]ketanserin from 5HT2A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300166(Ethyl 5-(3-(4-(3-chlorophenyl)piperazin-1-yl)propo...)
Affinity DataKi:  1.07E+3nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 in rat striatum by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300165(Ethyl 5-(3-(4-(3,4-dichlorophenyl)piperazin-1-yl)p...)
Affinity DataKi:  3.61E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300164(Ethyl 5-(3-(4-o-tolylpiperazin-1-yl)propoxy)-1H-in...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300163(Ethyl 5-(3-(4-(2-cyanophenyl)piperazin-1-yl)propox...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300160(Ethyl 5-(3-(4-(4-methoxyphenyl)piperazin-1-yl)prop...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]ketanserin from 5HT2A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300168(Ethyl 5-(3-(4-(4-nitrophenyl)piperazin-1-yl)propox...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]ketanserin from 5HT2A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300170(Ethyl 5-(3-(4-(4-chlorophenyl)piperazin-1-yl)propo...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]ketanserin from 5HT2A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300166(Ethyl 5-(3-(4-(3-chlorophenyl)piperazin-1-yl)propo...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]ketanserin from 5HT2A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300159(Ethyl 5-(3-(4-((benzo[d][1,3]dioxol-5-yl)methyl)pi...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 in rat striatum by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300161(ethyl 5-(3-(4-(3,4-dichlorophenyl)piperazin-1-yl)p...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]mesulergine from 5HT2C in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300162(Ethyl 5-(3-(4-(2-chlorophenyl)piperazin-1-yl)propo...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300161(ethyl 5-(3-(4-(3,4-dichlorophenyl)piperazin-1-yl)p...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300160(Ethyl 5-(3-(4-(4-methoxyphenyl)piperazin-1-yl)prop...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50300159(Ethyl 5-(3-(4-((benzo[d][1,3]dioxol-5-yl)methyl)pi...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A in Sprague-Dawley rat brain cortex by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed