Compile Data Set for Download or QSAR
Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50030994
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304943(N-(2-hydroxy-2-phenylethyl)-6-(4-(2-(trifluorometh...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304955(N-(2-hydroxy-2-(thiophen-3-yl)ethyl)-6-(4-(2-methy...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304951(N-(2-(4-fluorophenyl)-2-hydroxyethyl)-6-(4-(2-meth...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304950(N-(2-(3-fluorophenyl)-2-hydroxyethyl)-6-(4-(2-meth...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304946(N-(2-hydroxy-2-phenylethyl)-6-(4-(3-(trifluorometh...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304937(N-phenethyl-6-(4-(2-(trifluoromethyl)benzoyl)piper...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304950(N-(2-(3-fluorophenyl)-2-hydroxyethyl)-6-(4-(2-meth...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304956(N-(2-hydroxy-2-(thiophen-2-yl)ethyl)-6-(4-(2-methy...)
Affinity DataIC50: 7nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304955(N-(2-hydroxy-2-(thiophen-3-yl)ethyl)-6-(4-(2-methy...)
Affinity DataIC50: 7nMAssay Description:Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304951(N-(2-(4-fluorophenyl)-2-hydroxyethyl)-6-(4-(2-meth...)
Affinity DataIC50: 7nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304944(N-(2-hydroxy-2-phenylethyl)-6-(4-(2-methylbenzoyl)...)
Affinity DataIC50: 7nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304943(N-(2-hydroxy-2-phenylethyl)-6-(4-(2-(trifluorometh...)
Affinity DataIC50: 7nMAssay Description:Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304937(N-phenethyl-6-(4-(2-(trifluoromethyl)benzoyl)piper...)
Affinity DataIC50: 9nMAssay Description:Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304949(N-(2-(2-fluorophenyl)-2-hydroxyethyl)-6-(4-(2-meth...)
Affinity DataIC50: 9nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304946(N-(2-hydroxy-2-phenylethyl)-6-(4-(3-(trifluorometh...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304950(N-(2-(3-fluorophenyl)-2-hydroxyethyl)-6-(4-(2-meth...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human Scd1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleate pretreated for 30 mins measured after 4 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304943(N-(2-hydroxy-2-phenylethyl)-6-(4-(2-(trifluorometh...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human Scd1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleate pretreated for 30 mins measured after 4 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304944(N-(2-hydroxy-2-phenylethyl)-6-(4-(2-methylbenzoyl)...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304955(N-(2-hydroxy-2-(thiophen-3-yl)ethyl)-6-(4-(2-methy...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human Scd1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleate pretreated for 30 mins measured after 4 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304951(N-(2-(4-fluorophenyl)-2-hydroxyethyl)-6-(4-(2-meth...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human Scd1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleate pretreated for 30 mins measured after 4 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304949(N-(2-(2-fluorophenyl)-2-hydroxyethyl)-6-(4-(2-meth...)
Affinity DataIC50: 22nMAssay Description:Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304956(N-(2-hydroxy-2-(thiophen-2-yl)ethyl)-6-(4-(2-methy...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human Scd1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleate pretreated for 30 mins measured after 4 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304941((R)-N-(2-hydroxy-2-phenylethyl)-6-(4-(2-(trifluoro...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304941((R)-N-(2-hydroxy-2-phenylethyl)-6-(4-(2-(trifluoro...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304953(N-(2-hydroxy-2-(pyridin-3-yl)ethyl)-6-(4-(2-methyl...)
Affinity DataIC50: 28nMAssay Description:Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304954(N-(2-hydroxy-2-(pyridin-4-yl)ethyl)-6-(4-(2-methyl...)
Affinity DataIC50: 34nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304953(N-(2-hydroxy-2-(pyridin-3-yl)ethyl)-6-(4-(2-methyl...)
Affinity DataIC50: 37nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304953(N-(2-hydroxy-2-(pyridin-3-yl)ethyl)-6-(4-(2-methyl...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human Scd1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleate pretreated for 30 mins measured after 4 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304956(N-(2-hydroxy-2-(thiophen-2-yl)ethyl)-6-(4-(2-methy...)
Affinity DataIC50: 44nMAssay Description:Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304944(N-(2-hydroxy-2-phenylethyl)-6-(4-(2-methylbenzoyl)...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human Scd1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleate pretreated for 30 mins measured after 4 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304945(N-(2-hydroxy-2-phenylethyl)-6-(4-(2-methoxybenzoyl...)
Affinity DataIC50: 52nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304949(N-(2-(2-fluorophenyl)-2-hydroxyethyl)-6-(4-(2-meth...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human Scd1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleate pretreated for 30 mins measured after 4 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304942((S)-N-(2-hydroxy-2-phenylethyl)-6-(4-(2-(trifluoro...)
Affinity DataIC50: 66nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304941((R)-N-(2-hydroxy-2-phenylethyl)-6-(4-(2-(trifluoro...)
Affinity DataIC50: 71nMAssay Description:Inhibition of human Scd1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleate pretreated for 30 mins measured after 4 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304948(6-(4-(4-fluorobenzoyl)piperidin-1-yl)-N-(2-hydroxy...)
Affinity DataIC50: 74nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304948(6-(4-(4-fluorobenzoyl)piperidin-1-yl)-N-(2-hydroxy...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human Scd1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleate pretreated for 30 mins measured after 4 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304942((S)-N-(2-hydroxy-2-phenylethyl)-6-(4-(2-(trifluoro...)
Affinity DataIC50: 81nMAssay Description:Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304942((S)-N-(2-hydroxy-2-phenylethyl)-6-(4-(2-(trifluoro...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human Scd1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleate pretreated for 30 mins measured after 4 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304952(N-(2-hydroxy-2-(pyridin-2-yl)ethyl)-6-(4-(2-methyl...)
Affinity DataIC50: 95nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304939(N-phenethyl-6-(4-(2-(trifluoromethyl)benzoyl)piper...)
Affinity DataIC50: 99nMAssay Description:Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304946(N-(2-hydroxy-2-phenylethyl)-6-(4-(3-(trifluorometh...)
Affinity DataIC50: 103nMAssay Description:Inhibition of human Scd1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleate pretreated for 30 mins measured after 4 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304947(6-(4-benzoylpiperidin-1-yl)-N-(2-hydroxy-2-phenyle...)
Affinity DataIC50: 108nMAssay Description:Inhibition of human Scd1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleate pretreated for 30 mins measured after 4 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304948(6-(4-(4-fluorobenzoyl)piperidin-1-yl)-N-(2-hydroxy...)
Affinity DataIC50: 118nMAssay Description:Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304954(N-(2-hydroxy-2-(pyridin-4-yl)ethyl)-6-(4-(2-methyl...)
Affinity DataIC50: 144nMAssay Description:Inhibition of human Scd1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleate pretreated for 30 mins measured after 4 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304940(N-phenethyl-4-(4-(2-(trifluoromethyl)benzoyl)piper...)
Affinity DataIC50: 150nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304947(6-(4-benzoylpiperidin-1-yl)-N-(2-hydroxy-2-phenyle...)
Affinity DataIC50: 153nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304952(N-(2-hydroxy-2-(pyridin-2-yl)ethyl)-6-(4-(2-methyl...)
Affinity DataIC50: 180nMAssay Description:Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304954(N-(2-hydroxy-2-(pyridin-4-yl)ethyl)-6-(4-(2-methyl...)
Affinity DataIC50: 187nMAssay Description:Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304939(N-phenethyl-6-(4-(2-(trifluoromethyl)benzoyl)piper...)
Affinity DataIC50: 194nMAssay Description:Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50304938(N-phenethyl-5-(4-(2-(trifluoromethyl)benzoyl)piper...)
Affinity DataIC50: 250nMAssay Description:Inhibition of Scd1 in human HEK293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
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