Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50030679
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300041(7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl...)
Affinity DataKd:  23nMAssay Description:Binding affinity to G9a by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300041(7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl...)
Affinity DataIC50: 15nMAssay Description:Inhibition of G9a by Thioglo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300041(7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of GLP by Thioglo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300041(7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl...)
Affinity DataIC50: 58nMAssay Description:Inhibition of GLP by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 110nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300030(6,7-dimethoxy-2-(4-methylpiperazin-1-yl)-N-(1-meth...)
Affinity DataIC50: 200nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300029(6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-...)
Affinity DataIC50: 230nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 290nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300029(6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-...)
Affinity DataIC50: 330nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300031(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-(piperi...)
Affinity DataIC50: 510nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300031(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-(piperi...)
Affinity DataIC50: 550nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300030(6,7-dimethoxy-2-(4-methylpiperazin-1-yl)-N-(1-meth...)
Affinity DataIC50: 680nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 700nMAssay Description:Inhibition of GLPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300032(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...)
Affinity DataIC50: 810nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300034(6,7-dimethoxy-N2,N2-dimethyl-N4-(1-methylpiperidin...)
Affinity DataIC50: 900nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300033(N2,N2-diethyl-6,7-dimethoxy-N4-(1-methylpiperidin-...)
Affinity DataIC50: 910nMAssay Description:Inhibition of G9a by Thioglo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300034(6,7-dimethoxy-N2,N2-dimethyl-N4-(1-methylpiperidin...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300032(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of G9a by Thioglo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300028(N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-meth...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of G9aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300038(N-cyclopropyl-6,7-dimethoxy-2-(4-methyl-1,4-diazep...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300039(N-isopropyl-6,7-dimethoxy-2-(4-methyl-1,4-diazepan...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300033(N2,N2-diethyl-6,7-dimethoxy-N4-(1-methylpiperidin-...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300040(2-chloro-6,7-dimethoxy-N-(1-methylpiperidin-4-yl)q...)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300037(N-cyclohexyl-6,7-dimethoxy-2-(4-methyl-1,4-diazepa...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300036(6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(te...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300035(6,7-Dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(pi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed