Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50030667
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299858(1-(3,4-Dimethoxyphenyl)-N-(3-(5-methyl-1H-imidazol...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299853(1-(3,4-Dimethoxyphenyl)-3-(3-(5-methyl-1H-imidazol...)
Affinity DataKi:  6.30nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299845(3-[3-(5-Methyl-1H-imidazol-1-yl)propyl]-2-thioxo-2...)
Affinity DataKi:  17nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299844(2,3-Dihydro-3-(3-(5-methyl-1H-imidazol-1-yl)propyl...)
Affinity DataKi:  18nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299847(6-Benzyl-2,3-dihydro-3-(3-(5-methyl-1H-imidazol-1-...)
Affinity DataKi:  20nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299866(CHEMBL578153 | US8772508, 6 | N-(1-(3-(5-Methyl-1H...)
Affinity DataKi:  34nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299846(3-[3-(5-Methyl-1H-imidazol-1-yl)propyl]-2-thioxo-2...)
Affinity DataKi:  39nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299850(1-(3,4-Dimethoxyphenyl)-N-(3-(4-methyl-1H-imidazol...)
Affinity DataKi:  41nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299867(CHEMBL565907 | US8772508, 10 | N-(1-(3-(5-Methyl-1...)
Affinity DataKi:  42nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299864(US8772508, 1 | CHEMBL574357 | N-(1-(3-(5-Methyl-1H...)
Affinity DataKi:  44nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299865(US8772508, 7 | CHEMBL567406 | N-(-1-(3-(5-Methyl-1...)
Affinity DataKi:  51nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM7918(PBD150 | 1-(3-(1H-Imidazol-1-yl)propyl)-3-(3,4-dim...)
Affinity DataKi:  60nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299849(1-(3,4-Dimethoxyphenyl)-3-(3-(4-methyl-1H-imidazol...)
Affinity DataKi:  60nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299863(2-Cyano(3,4,5-trimethoxyphenyl)-3-(3-(5-methyl-1H-...)
Affinity DataKi:  61nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299861(2-Cyano-1-[3-(5-methyl-1H-imidazol-1-yl)propyl]-4-...)
Affinity DataKi:  65nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299868(US8772508, 5 | CHEMBL565908 | N-(1-(3-(5-Methyl-1H...)
Affinity DataKi:  67nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299859(2-Cyano(3-(5-methyl-1H-imidazol-1-yl)propyl)-3-(3,...)
Affinity DataKi:  82nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299848(2,3-Dihydro-6-methyl-3-(3-(5-methyl-1H-imidazol-1-...)
Affinity DataKi:  83nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM7937(N-(3-(1H-Imidazol-1-yl)propyl)-1-(3,4-dimethoxyphe...)
Affinity DataKi:  90nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299862((3-(5-Methyl-1H-imidazol-1-yl)propyl)-2-cyano-3-(2...)
Affinity DataKi:  130nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299843(2,3-Dihydro-3-(3-(4-methyl-1H-imidazol-1-yl)propyl...)
Affinity DataKi:  230nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299860((3,4-Dichlorophenyl)-2-cyano-3-(3-(5-methyl-1H-imi...)
Affinity DataKi:  253nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299838(3-(3-(1H-Imidazol-1-yl)propyl)-2,3-dihydro-2-thiox...)
Affinity DataKi:  300nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299840(3-[3-(1H-Imidazol-1-yl)propyl]-2-thioxo-2,3,5,6,7,...)
Affinity DataKi:  340nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299839(3-(3-(1H-Imidazol-1-yl)propyl)-2,3-dihydro-7-methy...)
Affinity DataKi:  360nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299830(N-(3-(1H-Imidazol-1-yl)propyl)-N-cyclohexyl-2-nitr...)
Affinity DataKi:  500nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299834(N-(1-(3-(1H-Imidazol-1-yl)propylamino)-2-nitroviny...)
Affinity DataKi:  520nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299837(N-(1-(3-(1H-Imidazol-1-yl)propylamino)-2-nitroviny...)
Affinity DataKi:  540nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299833(N-(1-(3-(1H-Imidazol-1-yl)propylamino)-2-nitroviny...)
Affinity DataKi:  540nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299832(N-(1-(3-(1H-Imidazol-1-yl)propylamino)-2-nitroviny...)
Affinity DataKi:  570nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299836(N-(-1-(3-(1H-Imidazol-1-yl)propylamino)-2-nitrovin...)
Affinity DataKi:  610nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299828((3-(1H-Imidazol-1-yl)propyl)-2-cyano-3-(2,3-dihydr...)
Affinity DataKi:  620nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299841(3-[3-(1H-Imidazol-1-yl)propyl]-2-thioxo-1,2,3,5,6,...)
Affinity DataKi:  620nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299826((3-(1H-Imidazol-1-yl)propyl)-2-cyano-3-(4-methoxyp...)
Affinity DataKi:  700nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299825((3-(1H-Imidazol-1-yl)propyl)-2-cyano-3-(4-isopropy...)
Affinity DataKi:  830nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299842(3-[3-(1H-Imidazol-1-yl)propyl]-2-thioxo-2,3,5,6,7,...)
Affinity DataKi:  900nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299856((3-(1H-Imidazol-1-yl)propyl)-2-cyano-3-phenylguani...)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299835(N-(1-(3-(1H-Imidazol-1-yl)propylamino)-2-nitroviny...)
Affinity DataKi:  1.03E+3nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299857((3-(1H-Imidazol-1-yl)propyl)-3-(4-bromophenyl)-2-c...)
Affinity DataKi:  1.09E+3nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299831(N-(1-(3-(1H-Imidazol-1-yl)propylamino)-2-nitroviny...)
Affinity DataKi:  1.17E+3nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299852(CHEMBL568073 | US8772508, 13 | N-(1-(3-(4-Methyl-1...)
Affinity DataKi:  1.29E+3nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299827((3-(1H-Imidazol-1-yl)propyl)-2-cyano-3-(3,4-dimeth...)
Affinity DataKi:  1.36E+3nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299855((3-(1H-Imidazol-1-yl)propyl)-2-cyano-3-(cyclopropy...)
Affinity DataKi:  1.37E+3nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299854((3-(1H-Imidazol-1-yl)propyl)-2-cyano-3-methylguani...)
Affinity DataKi:  1.53E+3nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299851((3-(4-Methyl-1H-imidazol-1-yl)propyl)-2-cyano-3-(2...)
Affinity DataKi:  1.65E+3nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299824((3-(1H-Imidazol-1-yl)propyl)-2-cyano-3-(4-(trifluo...)
Affinity DataKi:  6.72E+3nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299829(N-(3-(1H-Imidazol-1-yl)propyl)-N-methyl-2-nitroeth...)
Affinity DataKi:  2.06E+4nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed