Compile Data Set for Download or QSAR
Report error Found 152 Enz. Inhib. hit(s) with all data for entry = 50030663
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299783(4-(2-fluoro-6-(3-fluorophenoxy)phenyl)piperidine |...)
Affinity DataEC50:  498nMAssay Description:Inhibition of dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299788(4-(2-(3-fluorophenoxy)phenyl)piperidine | CHEMBL58...)
Affinity DataEC50:  657nMAssay Description:Inhibition of dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299792(4-(3-fluoro-2-phenoxyphenyl)piperidine | CHEMBL583...)
Affinity DataEC50:  877nMAssay Description:Partial agonist activity at human 5HT1A expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299783(4-(2-fluoro-6-(3-fluorophenoxy)phenyl)piperidine |...)
Affinity DataEC50:  915nMAssay Description:Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299792(4-(3-fluoro-2-phenoxyphenyl)piperidine | CHEMBL583...)
Affinity DataEC50:  982nMAssay Description:Inhibition of dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299788(4-(2-(3-fluorophenoxy)phenyl)piperidine | CHEMBL58...)
Affinity DataEC50:  1.02E+3nMAssay Description:Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299798(4-(2-(3-chlorophenoxy)phenyl)piperidine | CHEMBL57...)
Affinity DataEC50:  1.15E+3nMAssay Description:Partial agonist activity at human 5HT1A expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299788(4-(2-(3-fluorophenoxy)phenyl)piperidine | CHEMBL58...)
Affinity DataEC50:  21nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299783(4-(2-fluoro-6-(3-fluorophenoxy)phenyl)piperidine |...)
Affinity DataEC50:  28nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299798(4-(2-(3-chlorophenoxy)phenyl)piperidine | CHEMBL57...)
Affinity DataEC50:  49nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299797(1-(2-(benzyloxy)phenyl)piperazine | CHEMBL582928)
Affinity DataEC50:  83nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299783(4-(2-fluoro-6-(3-fluorophenoxy)phenyl)piperidine |...)
Affinity DataEC50:  137nMAssay Description:Partial agonist activity at human 5HT1A expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299798(4-(2-(3-chlorophenoxy)phenyl)piperidine | CHEMBL57...)
Affinity DataEC50:  186nMAssay Description:Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299788(4-(2-(3-fluorophenoxy)phenyl)piperidine | CHEMBL58...)
Affinity DataEC50:  219nMAssay Description:Partial agonist activity at human 5HT1A expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299792(4-(3-fluoro-2-phenoxyphenyl)piperidine | CHEMBL583...)
Affinity DataEC50:  358nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299792(4-(3-fluoro-2-phenoxyphenyl)piperidine | CHEMBL583...)
Affinity DataEC50:  1.76E+3nMAssay Description:Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299798(4-(2-(3-chlorophenoxy)phenyl)piperidine | CHEMBL57...)
Affinity DataEC50:  1.88E+3nMAssay Description:Inhibition of dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299797(1-(2-(benzyloxy)phenyl)piperazine | CHEMBL582928)
Affinity DataEC50:  2.93E+3nMAssay Description:Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299797(1-(2-(benzyloxy)phenyl)piperazine | CHEMBL582928)
Affinity DataEC50:  5.21E+3nMAssay Description:Inhibition of dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299797(1-(2-(benzyloxy)phenyl)piperazine | CHEMBL582928)
Affinity DataEC50: >1.00E+4nMAssay Description:Partial agonist activity at human 5HT1A expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299799(4-(4,5-difluoro-2-(4-fluorophenoxy)phenyl)piperidi...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299799(4-(4,5-difluoro-2-(4-fluorophenoxy)phenyl)piperidi...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299789(4-(5-fluoro-2-(4-fluorobenzyloxy)phenyl)piperidine...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299789(4-(5-fluoro-2-(4-fluorobenzyloxy)phenyl)piperidine...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299800(4-(2-(3,4-dichlorobenzyloxy)-5-fluorophenyl)piperi...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299801(4-(2-(3-fluorophenoxy)-4-methylphenyl)piperidine |...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299796(4-(2-(2-fluoro-5-methylphenoxy)phenyl)piperidine |...)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299787(4-(2,4-difluorophenyl)-2-(2-(piperazin-1-yl)benzyl...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299798(4-(2-(3-chlorophenoxy)phenyl)piperidine | CHEMBL57...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299802(4-(3,4-dichlorophenyl)-2-(2-(piperazin-1-yl)benzyl...)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299803(4-(5-chloro-2-(4-fluorobenzyloxy)phenyl)piperidine...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299804(4-(2-fluoro-6-(4-fluorophenoxy)phenyl)piperidine |...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299793(1-(2-(4-fluorophenoxy)phenyl)piperazine | CHEMBL57...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299802(4-(3,4-dichlorophenyl)-2-(2-(piperazin-1-yl)benzyl...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299805(1-(2-(3-fluorophenoxy)phenyl)piperazine | CHEMBL57...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299786(4-(2-(benzyloxy)-3-fluorophenyl)piperidine | CHEMB...)
Affinity DataKi:  9nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299795(4-(2-(benzyloxy)-6-fluorophenyl)piperidine | CHEMB...)
Affinity DataKi:  9nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299788(4-(2-(3-fluorophenoxy)phenyl)piperidine | CHEMBL58...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299788(4-(2-(3-fluorophenoxy)phenyl)piperidine | CHEMBL58...)
Affinity DataKi:  11nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299798(4-(2-(3-chlorophenoxy)phenyl)piperidine | CHEMBL57...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299806(4-(2-(4-fluorophenoxy)phenyl)piperidine | CHEMBL58...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299807(1-(2-((3-fluorophenoxy)methyl)phenyl)piperazine | ...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299783(4-(2-fluoro-6-(3-fluorophenoxy)phenyl)piperidine |...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299792(4-(3-fluoro-2-phenoxyphenyl)piperidine | CHEMBL583...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299800(4-(2-(3,4-dichlorobenzyloxy)-5-fluorophenyl)piperi...)
Affinity DataKi:  20nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299783(4-(2-fluoro-6-(3-fluorophenoxy)phenyl)piperidine |...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50299806(4-(2-(4-fluorophenoxy)phenyl)piperidine | CHEMBL58...)
Affinity DataKi:  21nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299796(4-(2-(2-fluoro-5-methylphenoxy)phenyl)piperidine |...)
Affinity DataKi:  26nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299797(1-(2-(benzyloxy)phenyl)piperazine | CHEMBL582928)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299795(4-(2-(benzyloxy)-6-fluorophenyl)piperidine | CHEMB...)
Affinity DataKi:  28nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
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