Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 4811
TargetCarbonic anhydrase 6(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137675(CHEMBL308495 | N-(p-sulfamoylphenyl)-alpha-glycopy...)
Affinity DataKi:  0.560nM ΔG°:  -51.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2...)
Affinity DataKi:  0.640nM ΔG°:  -51.6kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM11638(N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sul...)
Affinity DataKi:  0.800nM ΔG°:  -51.1kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM82123(Brinzolamide, BRZ)
Affinity DataKi:  0.900nM ΔG°:  -50.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM82123(Brinzolamide, BRZ)
Affinity DataKi:  3nM ΔG°:  -47.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137676(CHEMBL74846 | N-(p-sulfamoylphenyl)-alpha-glycopyr...)
Affinity DataKi:  3.40nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137675(CHEMBL308495 | N-(p-sulfamoylphenyl)-alpha-glycopy...)
Affinity DataKi:  3.5nM ΔG°:  -47.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137675(CHEMBL308495 | N-(p-sulfamoylphenyl)-alpha-glycopy...)
Affinity DataKi:  5.10nM ΔG°:  -46.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM13054(Dorzolamide, DZA | (2R,4R)-4-(ethylamino)-2-methyl...)
Affinity DataKi:  9nM ΔG°:  -45.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM13054(Dorzolamide, DZA | (2R,4R)-4-(ethylamino)-2-methyl...)
Affinity DataKi:  10nM ΔG°:  -44.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137676(CHEMBL74846 | N-(p-sulfamoylphenyl)-alpha-glycopyr...)
Affinity DataKi:  10nM ΔG°:  -44.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2...)
Affinity DataKi:  10.1nM ΔG°:  -44.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  11nM ΔG°:  -44.7kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  12nM ΔG°:  -44.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137675(CHEMBL308495 | N-(p-sulfamoylphenyl)-alpha-glycopy...)
Affinity DataKi:  12nM ΔG°:  -44.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137676(CHEMBL74846 | N-(p-sulfamoylphenyl)-alpha-glycopyr...)
Affinity DataKi:  13nM ΔG°:  -44.3kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137676(CHEMBL74846 | N-(p-sulfamoylphenyl)-alpha-glycopyr...)
Affinity DataKi:  14nM ΔG°:  -44.1kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137675(CHEMBL308495 | N-(p-sulfamoylphenyl)-alpha-glycopy...)
Affinity DataKi:  15nM ΔG°:  -43.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137675(CHEMBL308495 | N-(p-sulfamoylphenyl)-alpha-glycopy...)
Affinity DataKi:  16nM ΔG°:  -43.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2...)
Affinity DataKi:  18nM ΔG°:  -43.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2...)
Affinity DataKi:  23nM ΔG°:  -42.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2...)
Affinity DataKi:  25nM ΔG°:  -42.7kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2...)
Affinity DataKi:  34.1nM ΔG°:  -41.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM11638(N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sul...)
Affinity DataKi:  40nM ΔG°:  -41.5kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  250nM ΔG°:  -37.1kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137676(CHEMBL74846 | N-(p-sulfamoylphenyl)-alpha-glycopyr...)
Affinity DataKi:  510nM ΔG°:  -35.3kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137675(CHEMBL308495 | N-(p-sulfamoylphenyl)-alpha-glycopy...)
Affinity DataKi:  630nM ΔG°:  -34.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137676(CHEMBL74846 | N-(p-sulfamoylphenyl)-alpha-glycopyr...)
Affinity DataKi:  680nM ΔG°:  -34.6kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137675(CHEMBL308495 | N-(p-sulfamoylphenyl)-alpha-glycopy...)
Affinity DataKi:  750nM ΔG°:  -34.4kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137675(CHEMBL308495 | N-(p-sulfamoylphenyl)-alpha-glycopy...)
Affinity DataKi:  840nM ΔG°:  -34.1kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2...)
Affinity DataKi:  930nM ΔG°:  -33.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2...)
Affinity DataKi:  1.00E+3nM ΔG°:  -33.7kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2...)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM11638(N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sul...)
Affinity DataKi:  1.20E+4nM ΔG°:  -27.6kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM82123(Brinzolamide, BRZ)
Affinity DataKi:  4.50E+4nM ΔG°:  -24.4kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM13054(Dorzolamide, DZA | (2R,4R)-4-(ethylamino)-2-methyl...)
Affinity DataKi:  5.00E+4nM ΔG°:  -24.1kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2011
Entry Details Article
PubMed