Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50031336
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataIC50: 3nMAssay Description:Inhibition of HER2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311465(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-3-me...)
Affinity DataIC50: 4nMAssay Description:Inhibition of HER2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311462(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-N-(2...)
Affinity DataIC50: 7nMAssay Description:Inhibition of HER2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 15nMAssay Description:Inhibition of EGFR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataIC50: 19nMAssay Description:Inhibition of EGFR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataIC50: 124nMAssay Description:Inhibition of HER2 in human SKBR3 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataIC50: 140nMAssay Description:Inhibition of EGFR in human A431 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311464(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-3-me...)
Affinity DataIC50: 257nMAssay Description:Inhibition of EGFR in human A431 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 420nMAssay Description:Inhibition of EGFR in human A431 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311469(7-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-N-(2...)
Affinity DataIC50: 620nMAssay Description:Inhibition of HER2 in human SKBR3 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311464(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-3-me...)
Affinity DataIC50: 843nMAssay Description:Inhibition of HER2 in human SKBR3 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311466(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-...)
Affinity DataIC50: 867nMAssay Description:Inhibition of EGFR in human A431 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311467(ethyl 4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino...)
Affinity DataIC50: 934nMAssay Description:Inhibition of HER2 in human SKBR3 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311462(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-N-(2...)
Affinity DataIC50: 960nMAssay Description:Inhibition of HER2 in human SKBR3 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311463(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-3-me...)
Affinity DataIC50: 980nMAssay Description:Inhibition of EGFR in human A431 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311462(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-N-(2...)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of EGFR in human A431 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311467(ethyl 4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino...)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of EGFR in human A431 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311462(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-N-(2...)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of EGFR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of HER2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of HER2 in human SKBR3 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311463(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-3-me...)
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of HER2 in human SKBR3 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311468(7-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-N-(2...)
Affinity DataIC50: 3.84E+3nMAssay Description:Inhibition of HER2 in human SKBR3 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311466(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HER2 in human SKBR3 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311465(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-3-me...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HER2 in human SKBR3 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311465(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-3-me...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of EGFR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311463(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-3-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311469(7-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-N-(2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311468(7-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-N-(2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311467(ethyl 4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311466(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311464(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-3-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311465(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-3-me...)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of EGFR in human A431 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311469(7-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-N-(2...)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of EGFR in human A431 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Hengrui Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311468(7-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-N-(2...)
Affinity DataIC50: 7.72E+4nMAssay Description:Inhibition of EGFR in human A431 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed