Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50030628
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299378(N4-(2,3-dihydro-1H-inden-2-yl)-2-(piperazin-1-yl)-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299360(N2-(2,3-dihydro-1H-inden-2-yl)-6-(piperazin-1-yl)-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299374((R)-N2-(2,3-dihydro-1H-inden-2-yl)-6-(3-methylpipe...)
Affinity DataIC50: 8nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299366(4-(2,3-dihydro-1H-inden-2-yloxy)-6-(piperazin-1-yl...)
Affinity DataIC50: 8nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299372(6-(1,4-diazepan-1-yl)-N2-(2,3-dihydro-1H-inden-2-y...)
Affinity DataIC50: 11nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299378(N4-(2,3-dihydro-1H-inden-2-yl)-2-(piperazin-1-yl)-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of ROCK1 in human THP1 cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299379(N4-(2,3-dihydro-1H-inden-2-yl)-6-(piperazin-1-yl)-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299372(6-(1,4-diazepan-1-yl)-N2-(2,3-dihydro-1H-inden-2-y...)
Affinity DataIC50: 17nMAssay Description:Inhibition of ROCK1 in human THP1 cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299364(6-(piperazin-1-yl)-N2-(pyridin-4-yl)-N4-(1,2,3,4-t...)
Affinity DataIC50: 23nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299374((R)-N2-(2,3-dihydro-1H-inden-2-yl)-6-(3-methylpipe...)
Affinity DataIC50: 26nMAssay Description:Inhibition of ROCK1 in human THP1 cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299360(N2-(2,3-dihydro-1H-inden-2-yl)-6-(piperazin-1-yl)-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of ROCK1 in human THP1 cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299366(4-(2,3-dihydro-1H-inden-2-yloxy)-6-(piperazin-1-yl...)
Affinity DataIC50: 57nMAssay Description:Inhibition of ROCK1 in human THP1 cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299373(N2-(2,3-dihydro-1H-inden-2-yl)-N4-methyl-N4-(2-(me...)
Affinity DataIC50: 81nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299377((S)-N2-(2,3-dihydro-1H-inden-2-yl)-6-(2-methylpipe...)
Affinity DataIC50: 87nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299376((R)-N2-(2,3-dihydro-1H-inden-2-yl)-6-(2-methylpipe...)
Affinity DataIC50: 118nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299375((S)-N2-(2,3-dihydro-1H-inden-2-yl)-6-(3-methylpipe...)
Affinity DataIC50: 135nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299379(N4-(2,3-dihydro-1H-inden-2-yl)-6-(piperazin-1-yl)-...)
Affinity DataIC50: 154nMAssay Description:Inhibition of ROCK1 in human THP1 cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299365(N2-(2,3-dihydro-1H-inden-1-yl)-6-(piperazin-1-yl)-...)
Affinity DataIC50: 185nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299371(N2-(2,3-dihydro-1H-inden-2-yl)-6-(4-methylpiperazi...)
Affinity DataIC50: 305nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299362(N2-phenethyl-6-(piperazin-1-yl)-N4-(pyridin-4-yl)-...)
Affinity DataIC50: 326nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299363(N2-benzyl-6-(piperazin-1-yl)-N4-(pyridin-4-yl)-1,3...)
Affinity DataIC50: 400nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299361(N2-cyclopentyl-6-(piperazin-1-yl)-N4-(pyridin-4-yl...)
Affinity DataIC50: 890nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299368(N2-(2,3-dihydro-1H-inden-2-yl)-6-(piperazin-1-yl)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299380(N2-(2,3-dihydro-1H-inden-2-yl)-6-(piperazin-1-yl)-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299369(N2-(2,3-dihydro-1H-inden-2-yl)-N4-phenyl-6-(pipera...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299370(N2-(2,3-dihydro-1H-inden-2-yl)-6-(piperidin-1-yl)-...)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299367(N2-(2,3-dihydro-1H-inden-2-yl)-6-(piperazin-1-yl)-...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed