Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50030619
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM16047(EVNXXAEF | N-{(2R,4S,5S)-5-[(L-alpha-glutamyl-L-va...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50299244(N1-((2S,3S)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataKi:  10nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50299239(N-(4-Fluorophenyl)-11-oxo-10,11-dihydro-5H-dibenzo...)
Affinity DataKi:  211nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50299243(3-(6-Fluoro-1H-benzo[d]imidazol-2-yl)-5H-dibenzo[b...)
Affinity DataKi:  244nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50299241(3-(5-(4-Fluorophenyl)-1H-imidazol-2-yl)-5H dibenzo...)
Affinity DataKi:  293nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50299238(Methyl 11-Oxo-N-(pyridin-4-yl)-10,11-dihydro-5H-di...)
Affinity DataKi:  295nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50299242(3-(3H-Imidazo[4,5-c]pyridin-2-yl)-5H-dibenzo[b,e][...)
Affinity DataKi:  309nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50299240(3-(5-(Pyridin-4-yl)-1H-imidazol-2-yl)-5H dibenzo[b...)
Affinity DataKi:  348nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed