Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 3417
LigandChemical structure of BindingDB Monomer ID 33294BDBM33294(phenylpropanoic acid derivative, 17j)
Affinity DataIC50: 3nM EC50:  13nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysine SPA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33293BDBM33293(racemic | phenylpropanoic acid derivative, 17i)
Affinity DataIC50: 5nM EC50:  15nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysine SPA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33293BDBM33293(racemic | phenylpropanoic acid derivative, 17i)
Affinity DataIC50: 24nM EC50:  182nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33294BDBM33294(phenylpropanoic acid derivative, 17j)
Affinity DataIC50: 34nM EC50:  61nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33289BDBM33289(phenylpropanoic acid derivative, 17e)
Affinity DataIC50: 145nM EC50:  65nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysine SPA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33284BDBM33284(BMC164883 Compound 53 | phenylpropanoic acid deriv...)
Affinity DataIC50: 185nM EC50:  140nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysine SPA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28681BDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataIC50: 274nM EC50:  223nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysine SPA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33288BDBM33288(racemic | phenylpropanoic acid derivative, 17d)
Affinity DataIC50: 327nM EC50:  228nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysine SPA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33285BDBM33285(racemic | phenylpropanoic acid derivative, 17a)
Affinity DataIC50: 1.60E+3nM EC50:  399nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysine SPA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33284BDBM33284(BMC164883 Compound 53 | phenylpropanoic acid deriv...)
Affinity DataIC50: 912nM EC50:  623nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33285BDBM33285(racemic | phenylpropanoic acid derivative, 17a)
Affinity DataIC50: 676nM EC50:  685nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33289BDBM33289(phenylpropanoic acid derivative, 17e)
Affinity DataIC50: 899nM EC50:  874nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33288BDBM33288(racemic | phenylpropanoic acid derivative, 17d)
Affinity DataIC50: 877nM EC50:  2.60E+3nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33287BDBM33287(racemic | phenylpropanoic acid derivative, 17c)
Affinity DataIC50: 1.60E+3nM EC50:  3.80E+3nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysine SPA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33286BDBM33286(racemic | phenylpropanoic acid derivative, 17b)
Affinity DataIC50: 1.40E+4nM EC50:  1.90E+3nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysine SPA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33295BDBM33295(phenylpropanoic acid derivative, 17k)
Affinity DataIC50: 3.30E+3nM EC50: >2.00E+4nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33296BDBM33296(BMC164883 Compound 58 | racemic | phenylpropanoic ...)
Affinity DataIC50: 3.30E+3nM EC50:  5.00E+3nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33296BDBM33296(BMC164883 Compound 58 | racemic | phenylpropanoic ...)
Affinity DataIC50: 4.00E+3nM EC50:  3.90E+3nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysine SPA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33286BDBM33286(racemic | phenylpropanoic acid derivative, 17b)
Affinity DataEC50:  5.70E+3nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33287BDBM33287(racemic | phenylpropanoic acid derivative, 17c)
Affinity DataEC50:  8.50E+3nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28681BDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataEC50: >1.20E+4nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33292BDBM33292(racemic | phenylpropanoic acid derivative, 17h)
Affinity DataIC50: 1.40E+4nM EC50: >3.00E+4nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysine SPA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33291BDBM33291(racemic | phenylpropanoic acid derivative, 17g)
Affinity DataIC50: 1.80E+4nM EC50: >3.00E+4nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysine SPA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33295BDBM33295(phenylpropanoic acid derivative, 17k)
Affinity DataIC50: 7.00E+4nM EC50: >2.00E+4nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysine SPA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33290BDBM33290(phenylpropanoic acid derivative, 17f)
Affinity DataIC50: 3.30E+4nM EC50: >2.00E+4nMpH: 7.4 T: 2°CAssay Description:Human 6His-PPAR ligand-binding domain was added to the mixture containing radioligand and test compound, followed by yttrium silicate polylysine SPA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33290BDBM33290(phenylpropanoic acid derivative, 17f)
Affinity DataEC50: >2.00E+4nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33291BDBM33291(racemic | phenylpropanoic acid derivative, 17g)
Affinity DataEC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 33292BDBM33292(racemic | phenylpropanoic acid derivative, 17h)
Affinity DataEC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed