Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50031329
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311312(N-(2-chlorophenyl)-6-phenylimidazo[1,2-a]pyridine-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311306(N-(2-chlorophenyl)-5-(piperidin-1-yl)pyrazolo[1,5-...)
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311302(N-(2-chlorophenyl)-5-phenylpyrazolo[1,5-a]pyridine...)
Affinity DataIC50: 66nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311303(N-(2-chlorophenyl)-5-(dimethylamino)pyrazolo[1,5-a...)
Affinity DataIC50: 77nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311316(LDN-211904 | N-(2-chlorophenyl)-6-(piperidin-4-yl)...)
Affinity DataIC50: 79nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311313(N-(2-chlorophenyl)-6-(piperidin-1-yl)imidazo[1,2-a...)
Affinity DataIC50: 87nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311318(6-bromo-N-(2-chlorophenyl)-2-methylimidazo[1,2-a]p...)
Affinity DataIC50: 173nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311301(N-(2-chlorophenyl)-5-methoxypyrazolo[1,5-a]pyridin...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311304(N-(2-chlorophenyl)-5-(1H-pyrrol-1-yl)pyrazolo[1,5-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311317(N-(2-chlorophenyl)-6-(4-hydroxypiperidin-4-yl)imid...)
Affinity DataIC50: 228nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311305(N-(2-chlorophenyl)-5-morpholinopyrazolo[1,5-a]pyri...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311296(N-(2-chlorophenyl)-5-methylpyrazolo[1,5-a]pyridine...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311311(N-(2-chlorophenyl)imidazo[1,2-a]pyridine-3-carboxa...)
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311288(N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carbox...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311299(5-chloro-N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311310(N-(2-chlorophenyl)pyrazolo[1,5-a]pyrazine-3-carbox...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311295(N-(2-chlorophenyl)-4-methylpyrazolo[1,5-a]pyridine...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311297(N-(2-chlorophenyl)-6-methylpyrazolo[1,5-a]pyridine...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311292(N-(2-cyanophenyl)pyrazolo[1,5-a]pyridine-3-carboxa...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311307(5-(benzyloxy)-N-(2-chlorophenyl)pyrazolo[1,5-a]pyr...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311308(N-(2-chlorophenyl)-1H-indazole-3-carboxamide | CHE...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311309(N-(2-chlorophenyl)-[1,2,3]triazolo[1,5-a]pyridine-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311294(2-chloro-N-(pyrazolo[1,5-a]pyridin-3-ylmethyl)anil...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311298(4-chloro-N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311291(N-(2-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyridi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311290(N-(2,3-dichlorophenyl)pyrazolo[1,5-a]pyridine-3-ca...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311314(N-(2-methoxyphenyl)-6-phenylimidazo[1,2-a]pyridine...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311315(N-(2-chlorophenyl)-2-methyl-6-phenylimidazo[1,2-a]...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311289(N-(2-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carbox...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311300(6-chloro-N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311293(2-chloro-N-(pyrazolo[1,5-a]pyridin-3-yl)benzamide ...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed