Compile Data Set for Download or QSAR
Report error Found 65 Enz. Inhib. hit(s) with all data for entry = 50030614
Target5-hydroxytryptamine receptor 1A(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 3nMAssay Description:Inhibition of 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 6nMAssay Description:Inhibition of 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 16nMAssay Description:Inhibition of 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299165((6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahyd...)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at human CXCR3 expressed in L1.2 cells assessed as inhibition of I-TAC-induced Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299173((6aR,9R)-N9,N9-diethyl-N7-o-tolyl-6,6a,8,9-tetrahy...)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at human CXCR3 expressed in L1.2 cells assessed as inhibition of I-TAC-induced Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299165((6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahyd...)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at mouse CXCR3 expressed in L1.2 cells assessed as inhibition of I-TAC-induced Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299174((6aR,9R)-N9,N9-diethyl-N7-m-tolyl-6,6a,8,9-tetrahy...)
Affinity DataIC50: 45nMAssay Description:Antagonist activity at human CXCR3 expressed in L1.2 cells assessed as inhibition of I-TAC-induced Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299165((6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahyd...)
Affinity DataIC50: 54nMAssay Description:Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 54nMAssay Description:Inhibition of 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299171((6aR,9R)-N9,N9-diethyl-4-methyl-N7-phenyl-6,6a,8,9...)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human CXCR3 expressed in L1.2 cells assessed as inhibition of I-TAC-induced Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299176((6aR,9R)-N9,N9-diethyl-N7-(pyridin-2-yl)-6,6a,8,9-...)
Affinity DataIC50: 62nMAssay Description:Antagonist activity at human CXCR3 expressed in L1.2 cells assessed as inhibition of I-TAC-induced Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299177((6aR,9R)-N9,N9-diethyl-N7-(pyridin-3-yl)-6,6a,8,9-...)
Affinity DataIC50: 67nMAssay Description:Antagonist activity at human CXCR3 expressed in L1.2 cells assessed as inhibition of I-TAC-induced Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299165((6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahyd...)
Affinity DataIC50: 74nMAssay Description:Antagonist activity at human CXCR3 expressed in L1.2 cells assessed as inhibition of I-TAC-induced cell migration by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299180((6aR,9R)-N7-cyclohexyl-N9,N9-diethyl-6,6a,8,9-tetr...)
Affinity DataIC50: 78nMAssay Description:Antagonist activity at human CXCR3 expressed in L1.2 cells assessed as inhibition of I-TAC-induced Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299175((6aR,9R)-N9,N9-diethyl-N7-p-tolyl-6,6a,8,9-tetrahy...)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human CXCR3 expressed in L1.2 cells assessed as inhibition of I-TAC-induced Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 143nMAssay Description:Inhibition of 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299173((6aR,9R)-N9,N9-diethyl-N7-o-tolyl-6,6a,8,9-tetrahy...)
Affinity DataIC50: 146nMAssay Description:Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299180((6aR,9R)-N7-cyclohexyl-N9,N9-diethyl-6,6a,8,9-tetr...)
Affinity DataIC50: 179nMAssay Description:Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299165((6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahyd...)
Affinity DataIC50: 200nMAssay Description:Displacement of [125I]I-TAC from mouse CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299165((6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahyd...)
Affinity DataIC50: 215nMAssay Description:Inhibition of adrenergic Alpha-2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299171((6aR,9R)-N9,N9-diethyl-4-methyl-N7-phenyl-6,6a,8,9...)
Affinity DataIC50: 220nMAssay Description:Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299174((6aR,9R)-N9,N9-diethyl-N7-m-tolyl-6,6a,8,9-tetrahy...)
Affinity DataIC50: 231nMAssay Description:Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299177((6aR,9R)-N9,N9-diethyl-N7-(pyridin-3-yl)-6,6a,8,9-...)
Affinity DataIC50: 285nMAssay Description:Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299175((6aR,9R)-N9,N9-diethyl-N7-p-tolyl-6,6a,8,9-tetrahy...)
Affinity DataIC50: 313nMAssay Description:Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299176((6aR,9R)-N9,N9-diethyl-N7-(pyridin-2-yl)-6,6a,8,9-...)
Affinity DataIC50: 428nMAssay Description:Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299172((6aR,9R)-4-benzyl-N9,N9-diethyl-N7-phenyl-6,6a,8,9...)
Affinity DataIC50: 510nMAssay Description:Antagonist activity at human CXCR3 expressed in L1.2 cells assessed as inhibition of I-TAC-induced Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299179((6aR,9R)-N9,N9-diethyl-N7-(3,4,5-trimethoxyphenyl)...)
Affinity DataIC50: 564nMAssay Description:Antagonist activity at human CXCR3 expressed in L1.2 cells assessed as inhibition of I-TAC-induced Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299172((6aR,9R)-4-benzyl-N9,N9-diethyl-N7-phenyl-6,6a,8,9...)
Affinity DataIC50: 590nMAssay Description:Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299165((6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahyd...)
Affinity DataIC50: 660nMAssay Description:Inhibition of dopamine D3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299165((6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahyd...)
Affinity DataIC50: 750nMAssay Description:Inhibition of 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299168((6aR,9R)-phenyl 9-(diethylcarbamoyl)-6,6a,8,9-tetr...)
Affinity DataIC50: 803nMAssay Description:Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299168((6aR,9R)-phenyl 9-(diethylcarbamoyl)-6,6a,8,9-tetr...)
Affinity DataIC50: 809nMAssay Description:Antagonist activity at human CXCR3 expressed in L1.2 cells assessed as inhibition of I-TAC-induced Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299165((6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahyd...)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299165((6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahyd...)
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299170((6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9,10,10a-h...)
Affinity DataIC50: 1.93E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in L1.2 cells assessed as inhibition of I-TAC-induced Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299178((6aR,9R)-N9,N9-diethyl-N7-(pyridin-4-yl)-6,6a,8,9-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299165((6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahyd...)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299179((6aR,9R)-N9,N9-diethyl-N7-(3,4,5-trimethoxyphenyl)...)
Affinity DataIC50: 3.05E+3nMAssay Description:Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299165((6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahyd...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299165((6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahyd...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299170((6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9,10,10a-h...)
Affinity DataIC50: 5.30E+3nMAssay Description:Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299165((6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahyd...)
Affinity DataIC50: 5.76E+3nMAssay Description:Inhibition of adrenergic beta-1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299178((6aR,9R)-N9,N9-diethyl-N7-(pyridin-4-yl)-6,6a,8,9-...)
Affinity DataIC50: 6.80E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in L1.2 cells assessed as inhibition of I-TAC-induced Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299165((6aR,9R)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahyd...)
Affinity DataIC50: 9.58E+3nMAssay Description:Inhibition of 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299169((6aR,9S)-9-((diethylamino)methyl)-N-phenyl-6,6a,8,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299181((6aR,9S)-N9,N9-diethyl-N7-phenyl-6,6a,8,9-tetrahyd...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of adrenergic beta-1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299167((6aR,9R)-N9,N9-diethyl-N7-methyl-N7-phenyl-6,6a,8,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human CXCR3 expressed in L1.2 cells assessed as inhibition of I-TAC-induced Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299167((6aR,9R)-N9,N9-diethyl-N7-methyl-N7-phenyl-6,6a,8,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
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