Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50030843
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302534((2R,3R)-N-(4-guanidinobutyl)-5-(3-(4-guanidinobuty...)
Affinity DataIC50: 2.90E+5nMAssay Description:Displacement of [3H]prazosin from rat salivary gland alpha1A adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302533((2S,3S)-N-(4-guanidinobutyl)-5-(3-(4-guanidinobuty...)
Affinity DataIC50: 3.10E+5nMAssay Description:Displacement of [3H]prazosin from rat salivary gland alpha1A adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302535((2R,3S)-N-(4-guanidinobutyl)-5-(3-(4-guanidinobuty...)
Affinity DataIC50: 4.20E+5nMAssay Description:Displacement of [3H]prazosin from rat salivary gland alpha1A adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302538((2R,3R)-methyl 5-(3-(4-guanidinobutylamino)-3-oxop...)
Affinity DataIC50: 5.60E+5nMAssay Description:Displacement of [3H]prazosin from rat salivary gland alpha1A adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302541(N-(4-guanidinobutyl)-3-(4-hydroxyphenyl)acrylamide...)
Affinity DataIC50: 1.00E+8nMAssay Description:Antagonist activity at rat alpha1A adrenoceptor assessed as inhibition of phenylephrine-induced contraction of caudal arteryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302540(3-((2R,3R)-3-(4-guanidinobutylcarbamoyl)-2-(4-hydr...)
Affinity DataIC50: 1.00E+8nMAssay Description:Antagonist activity at rat alpha1A adrenoceptor assessed as inhibition of phenylephrine-induced contraction of caudal arteryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302539(3-((2S,3S)-3-(4-guanidinobutylcarbamoyl)-2-(4-hydr...)
Affinity DataIC50: 1.00E+8nMAssay Description:Antagonist activity at rat alpha1A adrenoceptor assessed as inhibition of phenylephrine-induced contraction of caudal arteryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302538((2R,3R)-methyl 5-(3-(4-guanidinobutylamino)-3-oxop...)
Affinity DataIC50: 9.72E+6nMAssay Description:Antagonist activity at rat alpha1A adrenoceptor assessed as inhibition of phenylephrine-induced contraction of caudal arteryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302537((2S,3S)-methyl 5-(3-(4-guanidinobutylamino)-3-oxop...)
Affinity DataIC50: 4.22E+7nMAssay Description:Antagonist activity at rat alpha1A adrenoceptor assessed as inhibition of phenylephrine-induced contraction of caudal arteryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302536((2S,3R)-N-(4-guanidinobutyl)-5-(3-(4-guanidinobuty...)
Affinity DataIC50: 1.77E+7nMAssay Description:Antagonist activity at rat alpha1A adrenoceptor assessed as inhibition of phenylephrine-induced contraction of caudal arteryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302535((2R,3S)-N-(4-guanidinobutyl)-5-(3-(4-guanidinobuty...)
Affinity DataIC50: 4.90E+6nMAssay Description:Antagonist activity at rat alpha1A adrenoceptor assessed as inhibition of phenylephrine-induced contraction of caudal arteryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302534((2R,3R)-N-(4-guanidinobutyl)-5-(3-(4-guanidinobuty...)
Affinity DataIC50: 1.43E+7nMAssay Description:Antagonist activity at rat alpha1A adrenoceptor assessed as inhibition of phenylephrine-induced contraction of caudal arteryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302533((2S,3S)-N-(4-guanidinobutyl)-5-(3-(4-guanidinobuty...)
Affinity DataIC50: 1.93E+7nMAssay Description:Antagonist activity at rat alpha1A adrenoceptor assessed as inhibition of phenylephrine-induced contraction of caudal arteryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302541(N-(4-guanidinobutyl)-3-(4-hydroxyphenyl)acrylamide...)
Affinity DataIC50: 5.76E+7nMAssay Description:Displacement of [3H]prazosin from rat salivary gland alpha1A adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302540(3-((2R,3R)-3-(4-guanidinobutylcarbamoyl)-2-(4-hydr...)
Affinity DataIC50: 1.00E+8nMAssay Description:Displacement of [3H]prazosin from rat salivary gland alpha1A adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302539(3-((2S,3S)-3-(4-guanidinobutylcarbamoyl)-2-(4-hydr...)
Affinity DataIC50: 1.00E+8nMAssay Description:Displacement of [3H]prazosin from rat salivary gland alpha1A adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302537((2S,3S)-methyl 5-(3-(4-guanidinobutylamino)-3-oxop...)
Affinity DataIC50: 2.16E+6nMAssay Description:Displacement of [3H]prazosin from rat salivary gland alpha1A adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302536((2S,3R)-N-(4-guanidinobutyl)-5-(3-(4-guanidinobuty...)
Affinity DataIC50: 2.44E+6nMAssay Description:Displacement of [3H]prazosin from rat salivary gland alpha1A adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed