Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50031481
TargetComplement factor B(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50314023((6S,9S,12S,15S,18S,21S)-21-acetamido-1,26-diamino-...)
Affinity DataIC50: 250nMpH: 9.5Assay Description:Inhibition of human complement factor B treated for 5 mins before addition of substrate Ac-SHLGLAR-pNA at pH 9.5 by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetComplement factor B(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50314024((6S,9S,12S,15S,18S,21S)-21-acetamido-1,26-diamino-...)
Affinity DataIC50: 600nMpH: 9.5Assay Description:Inhibition of human complement factor B treated for 5 mins before addition of substrate Ac-SHLGLAR-pNA at pH 9.5 by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetComplement factor B(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50314027((6S,9S,12S,15S,18S)-1-amino-1-imino-12,15,18-triis...)
Affinity DataIC50: 3.00E+3nMpH: 9.5Assay Description:Inhibition of human complement factor B treated for 5 mins before addition of substrate Ac-SHLGLAR-pNA at pH 9.5 by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetComplement factor B(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50314028((6S,9S,12S,15S,18S,21S)-21-((1H-imidazol-5-yl)meth...)
Affinity DataIC50: 3.00E+3nMpH: 9.5Assay Description:Inhibition of human complement factor B treated for 5 mins before addition of substrate Ac-SHLGLAR-pNA at pH 9.5 by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetComplement factor B(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50314033((6S,9S,12S,15S,18S,21S,24S)-21-((1H-imidazol-5-yl)...)
Affinity DataIC50: 4.00E+3nMpH: 9.5Assay Description:Inhibition of human complement factor B treated for 5 mins before addition of substrate Ac-SHLGLAR-pNA at pH 9.5 by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetComplement factor B(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50314031((6S,9S,12S,15S,18S,21S,24S)-21-((1H-imidazol-5-yl)...)
Affinity DataIC50: 5.00E+3nMpH: 9.5Assay Description:Inhibition of human complement factor B treated for 5 mins before addition of substrate Ac-SHLGLAR-pNA at pH 9.5 by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetComplement factor B(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50314032((2S,5S,8S,11S,14S,17S,20S)-17-((1H-imidazol-5-yl)m...)
Affinity DataIC50: 5.00E+3nMpH: 9.5Assay Description:Inhibition of human complement factor B treated for 5 mins before addition of substrate Ac-SHLGLAR-pNA at pH 9.5 by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetComplement factor B(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50314025((6S,12S,15S,18S,21S)-21-acetamido-1,26-diamino-1,2...)
Affinity DataIC50: 7.00E+3nMpH: 9.5Assay Description:Inhibition of human complement factor B treated for 5 mins before addition of substrate Ac-SHLGLAR-pNA at pH 9.5 by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetComplement factor B(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50314023((6S,9S,12S,15S,18S,21S)-21-acetamido-1,26-diamino-...)
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:Inhibition of human C3 convertase assessed as inhibition of C3a and C3b fragment production at pH 7.4 after 30 mins by SDS-PAGEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetComplement factor B(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50314026((6S,9S,12S,15S)-1-amino-1-imino-12,15-diisobutyl-9...)
Affinity DataIC50: 1.20E+4nMpH: 9.5Assay Description:Inhibition of human complement factor B treated for 5 mins before addition of substrate Ac-SHLGLAR-pNA at pH 9.5 by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetComplement factor B(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50241352(CHEMBL266963 | ICVVQDWGHHRCT-NH2 | 2-[(4R,7S,10S,1...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human C3/C5 convertase assessed as inhibition of C3 cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetComplement factor B(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50314030((6S,9S,12S,18S,21S,24S)-21-((1H-imidazol-5-yl)meth...)
Affinity DataIC50: 1.30E+4nMpH: 9.5Assay Description:Inhibition of human complement factor B treated for 5 mins before addition of substrate Ac-SHLGLAR-pNA at pH 9.5 by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetComplement factor B(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50314034((6S,9S,12S,18S,21S,24S)-21-((1H-imidazol-5-yl)meth...)
Affinity DataIC50: 1.90E+4nMpH: 9.5Assay Description:Inhibition of human complement factor B treated for 5 mins before addition of substrate Ac-SHLGLAR-pNA at pH 9.5 by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetComplement factor B(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50314035(Ac-SHLGLAR-pNA | (S)-2-[(S)-2-((S)-2-Acetylamino-3...)
Affinity DataIC50: 1.90E+4nMpH: 9.5Assay Description:Inhibition of human complement factor B at pH 9.5 by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetComplement factor B(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50314029((6S,9S,12S,18S,21S,24S)-21-((1H-imidazol-5-yl)meth...)
Affinity DataIC50: 2.30E+4nMpH: 9.5Assay Description:Inhibition of human complement factor B treated for 5 mins before addition of substrate Ac-SHLGLAR-pNA at pH 9.5 by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetComplement factor B(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50314024((6S,9S,12S,15S,18S,21S)-21-acetamido-1,26-diamino-...)
Affinity DataIC50: 5.00E+4nMpH: 7.4Assay Description:Inhibition of human C3 convertase assessed as inhibition of C3a and C3b fragment production at pH 7.4 after 30 mins by SDS-PAGEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed