Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50030735
TargetAdenosine receptor A2a(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM21190(CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [125I]Z241385 from human cloned adenosine A2A receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300681(2-(4-methoxyphenyl)-5-methyl-2H-pyrazolo[4,3-d]pyr...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300681(2-(4-methoxyphenyl)-5-methyl-2H-pyrazolo[4,3-d]pyr...)
Affinity DataKi:  5.20nMAssay Description:Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300684(5-methyl-2-p-tolyl-2H-pyrazolo[4,3-d]pyrimidin-7(6...)
Affinity DataKi:  10nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300682(5-ethyl-2-(4-methoxyphenyl)-2H-pyrazolo[4,3-d]pyri...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300678(5-methyl-2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H...)
Affinity DataKi:  16nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM21190(CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...)
Affinity DataKi:  42nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated [3H]cAMP production by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300684(5-methyl-2-p-tolyl-2H-pyrazolo[4,3-d]pyrimidin-7(6...)
Affinity DataKi:  46nMAssay Description:Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300679(5-ethyl-2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)...)
Affinity DataKi:  52nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300680(2-(4-methoxyphenyl)-2H-pyrazolo[4,3-d]pyrimidin-7(...)
Affinity DataKi:  54nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300682(5-ethyl-2-(4-methoxyphenyl)-2H-pyrazolo[4,3-d]pyri...)
Affinity DataKi:  63nMAssay Description:Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300685(5-methyl-2-m-tolyl-2H-pyrazolo[4,3-d]pyrimidin-7(6...)
Affinity DataKi:  72nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300678(5-methyl-2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H...)
Affinity DataKi:  87nMAssay Description:Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM21190(CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...)
Affinity DataKi:  180nMAssay Description:Displacement of [125I]DPCPX from human cloned adenosine A1 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300677(2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one | C...)
Affinity DataKi:  185nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300679(5-ethyl-2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)...)
Affinity DataKi:  245nMAssay Description:Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300683(5-benzyl-2-(4-methoxyphenyl)-2H-pyrazolo[4,3-d]pyr...)
Affinity DataKi:  250nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300680(2-(4-methoxyphenyl)-2H-pyrazolo[4,3-d]pyrimidin-7(...)
Affinity DataKi:  270nMAssay Description:Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300685(5-methyl-2-m-tolyl-2H-pyrazolo[4,3-d]pyrimidin-7(6...)
Affinity DataKi:  354nMAssay Description:Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300677(2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one | C...)
Affinity DataKi:  725nMAssay Description:Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300683(5-benzyl-2-(4-methoxyphenyl)-2H-pyrazolo[4,3-d]pyr...)
Affinity DataKi:  850nMAssay Description:Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300686(5-benzyl-2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H...)
Affinity DataKi:  900nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed