Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50030948
TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50304361((E)-4-((1-(4-chlorobenzoyl)-3-methyl-5-oxo-4,5-dih...)
Affinity DataKd:  370nMAssay Description:Inhibition of pleckstrin homology domain of AKT by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50304362(4-((1-benzoyl-3-methyl-5-oxo-4,5-dihydro-1H-pyrazo...)
Affinity DataKd:  3.66E+3nMAssay Description:Inhibition of pleckstrin homology domain of AKT by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50304363(4-((1-(4-tert-butylbenzoyl)-3-methyl-5-oxo-4,5-dih...)
Affinity DataKd:  1.37E+3nMAssay Description:Inhibition of pleckstrin homology domain of AKT by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50304364(4-((1-(4-aminobenzoyl)-3-methyl-5-oxo-4,5-dihydro-...)
Affinity DataKd:  510nMAssay Description:Inhibition of pleckstrin homology domain of AKT by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50304365(4-((1-(4-hydroxybenzoyl)-3-methyl-5-oxo-4,5-dihydr...)
Affinity DataKd:  1.35E+3nMAssay Description:Inhibition of pleckstrin homology domain of AKT by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50304366(4-((1-(4-chlorobenzoyl)-3-methyl-5-oxo-4,5-dihydro...)
Affinity DataKd:  1.62E+3nMAssay Description:Inhibition of pleckstrin homology domain of AKT by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50304359((2R,3S,5S,6S)-6-(hydrogen phosphonato)-3,5-dihydro...)
Affinity DataKd:  1.50E+3nMAssay Description:Inhibition of pleckstrin homology domain of AKT by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50034417(4-amino-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamid...)
Affinity DataKd:  450nMAssay Description:Inhibition of pleckstrin homology domain of AKT by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50304368(N-(4-(N-1,3,4-thiadiazol-2-ylsulfamoyl)phenyl)deca...)
Affinity DataKd:  1.96E+4nMAssay Description:Inhibition of pleckstrin homology domain of AKT by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50304369(4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonam...)
Affinity DataKd:  4.08E+4nMAssay Description:Inhibition of pleckstrin homology domain of AKT by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50304369(4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonam...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of Akt phosphorylation in human BxPC3 cells by Western blottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50304368(N-(4-(N-1,3,4-thiadiazol-2-ylsulfamoyl)phenyl)deca...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Akt phosphorylation in human BxPC3 cells by Western blottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50034417(4-amino-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamid...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Akt phosphorylation in human BxPC3 cells by Western blottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50304367(N-(4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of pleckstrin homology domain of AKT by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50304371(N-(4-(N-1,3,4-thiadiazol-2-ylsulfamoyl)phenyl)-2-(...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Akt phosphorylation in human BxPC3 cells by Western blottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50304370(N-(4-(N-1,3,4-thiadiazol-2-ylsulfamoyl)phenyl)acet...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Akt phosphorylation in human BxPC3 cells by Western blottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The University of Texas

Curated by ChEMBL
LigandPNGBDBM50304360(benzene-1,2,3,4-tetrayl tetrakis(hydrogen phosphat...)
Affinity DataKi:  80nMAssay Description:Inhibition of pleckstrin homology domain of AKT by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)