Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50030726
TargetCytochrome P450 3A4(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50300539(N-((2R,3R)-2-(benzo[d][1,3]dioxol-5-yl)-3-((4S,5S)...)
Affinity DataKi:  30nMAssay Description:Inhibition of human recombinant CYP3A4 assessed as biotransformation of 7-benzyloxyquinoline to 7-hydroxyquinoline measured every 15 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50300543(((4S,5S)-5-((1R,2R)-3-benzamido-2-(benzo[d][1,3]di...)
Affinity DataKi:  70nMAssay Description:Inhibition of human recombinant CYP3A4 assessed as biotransformation of 7-benzyloxyquinoline to 7-hydroxyquinoline measured every 15 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50300538(N-((2R,3R)-2-(benzo[d][1,3]dioxol-5-yl)-3-((4S,5S)...)
Affinity DataKi:  170nMAssay Description:Inhibition of human recombinant CYP3A4 assessed as biotransformation of 7-benzyloxyquinoline to 7-hydroxyquinoline measured every 15 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50300541(tert-butyl(2R,3R)-2-(benzo[d][1,3]dioxol-5-yl)-3-(...)
Affinity DataKi:  320nMAssay Description:Inhibition of human recombinant CYP3A4 assessed as biotransformation of 7-benzyloxyquinoline to 7-hydroxyquinoline measured every 15 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50300542(N-((2R,3R)-2-(benzo[d][1,3]dioxol-5-yl)-3-((4S,5S)...)
Affinity DataKi:  580nMAssay Description:Inhibition of human recombinant CYP3A4 assessed as biotransformation of 7-benzyloxyquinoline to 7-hydroxyquinoline measured every 15 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50300544(((4S,5S)-5-((1R,2R)-3-benzamido-2-(benzo[d][1,3]di...)
Affinity DataKi:  1.01E+3nMAssay Description:Inhibition of human recombinant CYP3A4 assessed as biotransformation of 7-benzyloxyquinoline to 7-hydroxyquinoline measured every 15 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50300540(N-((2R,3R)-2-(benzo[d][1,3]dioxol-5-yl)-3-((4S,5S)...)
Affinity DataKi:  1.55E+3nMAssay Description:Inhibition of human recombinant CYP3A4 assessed as biotransformation of 7-benzyloxyquinoline to 7-hydroxyquinoline measured every 15 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed