Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50030724
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50300504(N-({3-[(5S)-5-tert-butyl-1-[(4-fluorophenyl)methyl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of HSV1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50300503(N-({3-[(5S)-5-tert-butyl-1-[(4-fluoro-3-methylphen...)
Affinity DataIC50: 3nMAssay Description:Inhibition of HSV1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50300502(N-({3-[(5S)-5-tert-butyl-1-[(4-fluorophenyl)methyl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of HSV1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50300497(N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydro...)
Affinity DataIC50: 3nMAssay Description:Inhibition of HSV1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50300499((S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydroxy-3-[...)
Affinity DataIC50: 4nMAssay Description:Inhibition of HSV1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50300498(N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-3-methyl-benzyl...)
Affinity DataIC50: 4nMAssay Description:Inhibition of HSV1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50300505(N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-3-methyl-benzyl...)
Affinity DataIC50: 5nMAssay Description:Inhibition of HSV1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50300496(N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydro...)
Affinity DataIC50: 5nMAssay Description:Inhibition of HSV1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50300501({3-[(S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydroxy...)
Affinity DataIC50: 6nMAssay Description:Inhibition of HSV1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50300500((S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydroxy-3-(...)
Affinity DataIC50: 9nMAssay Description:Inhibition of HSV1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM30491(1,1-dioxoisothiazole analog., 35)
Affinity DataIC50: 10nMAssay Description:Inhibition of HSV1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50300506((S)-5-tert-Butyl-3-[7-(1,1-dioxo-1lambda*6*-[1,2]t...)
Affinity DataIC50: 12nMAssay Description:Inhibition of HSV1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50300495(N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydro...)
Affinity DataIC50: 43nMAssay Description:Inhibition of HSV1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed