Compile Data Set for Download or QSAR
Report error Found 63 Enz. Inhib. hit(s) with all data for entry = 50030722
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300479(3-hydroxy-5-(4-(pyridin-4-yl)phenyl)pentanoic acid...)
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300470(3-hydroxy-5-(4'-(methylthio)biphenyl-4-yl)pentanoi...)
Affinity DataIC50: 58nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300471(5-(4'-acetylbiphenyl-4-yl)-3-hydroxypentanoic acid...)
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300472(5-(4'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid ...)
Affinity DataIC50: 86nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300480(5-(4-(benzofuran-2-yl)phenyl)-3-hydroxypentanoic a...)
Affinity DataIC50: 181nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 790nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 790nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300471(5-(4'-acetylbiphenyl-4-yl)-3-hydroxypentanoic acid...)
Affinity DataIC50: 970nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300470(3-hydroxy-5-(4'-(methylthio)biphenyl-4-yl)pentanoi...)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300469(5-(4-(9H-fluoren-2-yl)phenyl)-3-hydroxypentanoic a...)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300472(5-(4'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid ...)
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300473(2-(2-(biphenyl-4-yl)ethylsulfonyl)acetic acid | CH...)
Affinity DataIC50: 2.49E+3nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300481(5-(3'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid ...)
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300478(5-(biphenyl-4-yl)-3-methoxypentanoic acid | CHEMBL...)
Affinity DataIC50: 3.53E+3nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300466(5-(4'-(benzyloxy)biphenyl-4-yl)-3-hydroxypentanoic...)
Affinity DataIC50: 3.75E+3nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300479(3-hydroxy-5-(4-(pyridin-4-yl)phenyl)pentanoic acid...)
Affinity DataIC50: 3.76E+3nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300474(2-(2-(biphenyl-4-yl)ethylsulfinyl)acetic acid | CH...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of human recombinant MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300476(5-(biphenyl-4-yl)-3-oxopentanoic acid | CHEMBL5729...)
Affinity DataIC50: 7.84E+3nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300473(2-(2-(biphenyl-4-yl)ethylsulfonyl)acetic acid | CH...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300475(2-(2-(biphenyl-4-yl)ethylthio)acetic acid | CHEMBL...)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of human recombinant MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300467(3-hydroxy-5-(4'-phenoxybiphenyl-4-yl)pentanoic aci...)
Affinity DataIC50: 1.99E+4nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300468(5-(4-(dibenzo[b,d]furan-3-yl)phenyl)-3-hydroxypent...)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300469(5-(4-(9H-fluoren-2-yl)phenyl)-3-hydroxypentanoic a...)
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300468(5-(4-(dibenzo[b,d]furan-3-yl)phenyl)-3-hydroxypent...)
Affinity DataIC50: 3.35E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 3.66E+4nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 3.68E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 3.68E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300467(3-hydroxy-5-(4'-phenoxybiphenyl-4-yl)pentanoic aci...)
Affinity DataIC50: 4.19E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300480(5-(4-(benzofuran-2-yl)phenyl)-3-hydroxypentanoic a...)
Affinity DataIC50: 5.02E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300481(5-(3'-cyanobiphenyl-4-yl)-3-hydroxypentanoic acid ...)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300477(3-acetoxy-5-(biphenyl-4-yl)pentanoic acid | CHEMBL...)
Affinity DataIC50: 5.44E+4nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300475(2-(2-(biphenyl-4-yl)ethylthio)acetic acid | CHEMBL...)
Affinity DataIC50: 9.52E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300474(2-(2-(biphenyl-4-yl)ethylsulfinyl)acetic acid | CH...)
Affinity DataIC50: 9.59E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300478(5-(biphenyl-4-yl)-3-methoxypentanoic acid | CHEMBL...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300476(5-(biphenyl-4-yl)-3-oxopentanoic acid | CHEMBL5729...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300477(3-acetoxy-5-(biphenyl-4-yl)pentanoic acid | CHEMBL...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300466(5-(4'-(benzyloxy)biphenyl-4-yl)-3-hydroxypentanoic...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300469(5-(4-(9H-fluoren-2-yl)phenyl)-3-hydroxypentanoic a...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300468(5-(4-(dibenzo[b,d]furan-3-yl)phenyl)-3-hydroxypent...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300467(3-hydroxy-5-(4'-phenoxybiphenyl-4-yl)pentanoic aci...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300466(5-(4'-(benzyloxy)biphenyl-4-yl)-3-hydroxypentanoic...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300473(2-(2-(biphenyl-4-yl)ethylsulfonyl)acetic acid | CH...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
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