Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 3523
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35928(CHEMBL346230 | 3-(9,10-dihydroanthracen-9-yl)-N,N-...)
Affinity DataKi:  0.5nM ΔG°:  -53.1kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35927([3-(9,10-Dihydro-anthracen-9-yl)-propyl]-methyl-am...)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35925(9,10-dihydroanthracene(DHA), 2c)
Affinity DataKi:  6nM ΔG°:  -46.9kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

LigandPNGBDBM35927([3-(9,10-Dihydro-anthracen-9-yl)-propyl]-methyl-am...)
Affinity DataKi:  13nM ΔG°:  -44.7kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi:  20nM ΔG°:  -43.6kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

LigandPNGBDBM35928(CHEMBL346230 | 3-(9,10-dihydroanthracen-9-yl)-N,N-...)
Affinity DataKi:  22nM ΔG°:  -43.4kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35922(CHEMBL160933 | 1-(9,10-dihydroanthracen-9-yl)-N,N-...)
Affinity DataKi:  25nM ΔG°:  -43.4kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

LigandPNGBDBM35926(3-(9,10-Dihydro-anthracen-9-yl)-propylamine | CHEM...)
Affinity DataKi:  32nM ΔG°:  -42.5kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35924(9,10-dihydroanthracene(DHA), 2b)
Affinity DataKi:  48nM ΔG°:  -41.8kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

LigandPNGBDBM35921(1-(9,10-dihydroanthracen-9-yl)-N-methylmethanamine...)
Affinity DataKi:  52nM ΔG°:  -41.3kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35933(diphenylalkylamine (DPA), 5b)
Affinity DataKi:  64nM ΔG°:  -41.1kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35937(diphenylalkylamine (DPA), 6c)
Affinity DataKi:  70nM ΔG°:  -40.8kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35934(diphenylalkylamine (DPA), 5c)
Affinity DataKi:  75nM ΔG°:  -40.7kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

LigandPNGBDBM35925(9,10-dihydroanthracene(DHA), 2c)
Affinity DataKi:  84nM ΔG°:  -40.1kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

LigandPNGBDBM35924(9,10-dihydroanthracene(DHA), 2b)
Affinity DataKi:  92nM ΔG°:  -39.9kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35923(9-(2-aminoethyl)-9,10-dihydroanthracene | 2-(9,10-...)
Affinity DataKi:  137nM ΔG°:  -39.2kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35926(3-(9,10-Dihydro-anthracen-9-yl)-propylamine | CHEM...)
Affinity DataKi:  175nM ΔG°:  -38.6kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35921(1-(9,10-dihydroanthracen-9-yl)-N-methylmethanamine...)
Affinity DataKi:  189nM ΔG°:  -38.4kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi:  197nM ΔG°:  -38.3kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35936(diphenylalkylamine (DPA), 6b)
Affinity DataKi:  386nM ΔG°:  -36.6kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

LigandPNGBDBM35923(9-(2-aminoethyl)-9,10-dihydroanthracene | 2-(9,10-...)
Affinity DataKi:  480nM ΔG°:  -35.8kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

LigandPNGBDBM35922(CHEMBL160933 | 1-(9,10-dihydroanthracen-9-yl)-N,N-...)
Affinity DataKi:  540nM ΔG°:  -35.5kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

LigandPNGBDBM35936(diphenylalkylamine (DPA), 6b)
Affinity DataKi:  754nM ΔG°:  -34.7kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

LigandPNGBDBM35937(diphenylalkylamine (DPA), 6c)
Affinity DataKi:  1.15E+3nM ΔG°:  -33.7kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

LigandPNGBDBM35933(diphenylalkylamine (DPA), 5b)
Affinity DataKi:  1.50E+3nM ΔG°:  -33.0kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

LigandPNGBDBM35934(diphenylalkylamine (DPA), 5c)
Affinity DataKi:  1.64E+3nM ΔG°:  -32.8kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35935(diphenylalkylamine (DPA), 6a)
Affinity DataKi:  1.67E+3nM ΔG°:  -33.0kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

LigandPNGBDBM35935(diphenylalkylamine (DPA), 6a)
Affinity DataKi:  2.59E+3nM ΔG°:  -31.7kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35932(diphenylalkylamine (DPA), 5a)
Affinity DataKi:  2.76E+3nM ΔG°:  -31.7kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

LigandPNGBDBM35929(2,2-diphenylethylamine | CHEMBL10780 | 2,2-dipheny...)
Affinity DataKi:  4.61E+3nM ΔG°:  -30.3kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35931(2,2-diphenylethyl(dimethyl)amine;hydrochloride | d...)
Affinity DataKi:  5.17E+3nM ΔG°:  -30.2kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

LigandPNGBDBM35931(2,2-diphenylethyl(dimethyl)amine;hydrochloride | d...)
Affinity DataKi:  7.36E+3nM ΔG°:  -29.1kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

LigandPNGBDBM35930(diphenylalkylamine (DPA), 4b)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.3kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35929(2,2-diphenylethylamine | CHEMBL10780 | 2,2-dipheny...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35930(diphenylalkylamine (DPA), 4b)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

LigandPNGBDBM35932(diphenylalkylamine (DPA), 5a)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.3kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed