Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50030798
Target5-hydroxytryptamine receptor 1A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50146089(1,3-dimethyl-9-{3-[4-(2'-methoxyphenyl)-piperazin-...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cerebral cortex after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301634(7-Phenyl-8-[3-(N4-2'-methoxyphenyl)-piperazin-N1-y...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cerebral cortex after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301639(7-bromo-1,3-dimethyl-8-(3-(4-phenylpiperazin-1-yl)...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cerebral cortex after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301628(7-Methyl-8-[3-(N4-2'-methoxyphenyl)-piperazin-N1-y...)
Affinity DataKi:  16.8nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cerebral cortex after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301632(7-Methyl-8-[3-(N4-3'-chlorophenyl)-piperazin-N1-yl...)
Affinity DataKi:  17.1nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cerebral cortex after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301629(8-[3-(N4-phenyl)-piperazin-N1-yl-propyl]-1,3-dimet...)
Affinity DataKi:  24.8nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cerebral cortex after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301630(8-[3-(N4-2'-methoxyphenyl)-piperazin-N1-yl-propyl]...)
Affinity DataKi:  25.4nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cerebral cortex after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301627(7-Methyl-8-[3-(N4-phenyl)-piperazin-N1-yl-propyl]-...)
Affinity DataKi:  76.4nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cerebral cortex after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301631(8-[3-(N4-3'-chlorophenyl)-piperazin-N1-yl-propyl]-...)
Affinity DataKi:  91.5nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cerebral cortex after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301633(7-Phenyl-8-[3-(N4-phenyl)-piperazin-N1-yl-propyl]-...)
Affinity DataKi:  96.5nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cerebral cortex after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301634(7-Phenyl-8-[3-(N4-2'-methoxyphenyl)-piperazin-N1-y...)
Affinity DataKi:  143nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat striatum membrane after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301639(7-bromo-1,3-dimethyl-8-(3-(4-phenylpiperazin-1-yl)...)
Affinity DataKi:  297nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cerebral cortex after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301628(7-Methyl-8-[3-(N4-2'-methoxyphenyl)-piperazin-N1-y...)
Affinity DataKi:  345nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat striatum membrane after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301632(7-Methyl-8-[3-(N4-3'-chlorophenyl)-piperazin-N1-yl...)
Affinity DataKi:  403nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cerebral cortex after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301639(7-bromo-1,3-dimethyl-8-(3-(4-phenylpiperazin-1-yl)...)
Affinity DataKi:  414nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat striatum membrane after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50146089(1,3-dimethyl-9-{3-[4-(2'-methoxyphenyl)-piperazin-...)
Affinity DataKi:  486nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cerebral cortex after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301632(7-Methyl-8-[3-(N4-3'-chlorophenyl)-piperazin-N1-yl...)
Affinity DataKi:  767nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat striatum membrane after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301633(7-Phenyl-8-[3-(N4-phenyl)-piperazin-N1-yl-propyl]-...)
Affinity DataKi:  814nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cerebral cortex after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301630(8-[3-(N4-2'-methoxyphenyl)-piperazin-N1-yl-propyl]...)
Affinity DataKi:  839nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat striatum membrane after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301630(8-[3-(N4-2'-methoxyphenyl)-piperazin-N1-yl-propyl]...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cerebral cortex after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301628(7-Methyl-8-[3-(N4-2'-methoxyphenyl)-piperazin-N1-y...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cerebral cortex after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301629(8-[3-(N4-phenyl)-piperazin-N1-yl-propyl]-1,3-dimet...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cerebral cortex after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301629(8-[3-(N4-phenyl)-piperazin-N1-yl-propyl]-1,3-dimet...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat striatum membrane after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301638(N-2-[N4-(3-chloro)-phenyl-piperazin-N1-yl]-ethyl a...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cerebral cortex after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301637(N-2-[N4-(2-methoxy)-phenyl-piperazin-N1-yl]-ethyl ...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cerebral cortex after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301636(N-2-[(N4-phenyl)-piperazin-N1-yl]-ethyl amideof1,3...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cerebral cortex after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301635(7-Phenyl-8-[3-(N4-3'-chlorophenyl)-piperazin-N1-yl...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cerebral cortex after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301627(7-Methyl-8-[3-(N4-phenyl)-piperazin-N1-yl-propyl]-...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cerebral cortex after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301634(7-Phenyl-8-[3-(N4-2'-methoxyphenyl)-piperazin-N1-y...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cerebral cortex after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301633(7-Phenyl-8-[3-(N4-phenyl)-piperazin-N1-yl-propyl]-...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat striatum membrane after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301631(8-[3-(N4-3'-chlorophenyl)-piperazin-N1-yl-propyl]-...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cerebral cortex after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301627(7-Methyl-8-[3-(N4-phenyl)-piperazin-N1-yl-propyl]-...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat striatum membrane after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301631(8-[3-(N4-3'-chlorophenyl)-piperazin-N1-yl-propyl]-...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat striatum membrane after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed