Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50030925
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50304109(5'-Nitro-1H,1'H-[2,3']biindolylidene-3,2'-dione 3-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50304111(N-((Z)-3,2'-Dioxo-1,3,1',2'-tetrahydro-[2,3']biind...)
Affinity DataIC50: 18nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50304121((Z)-5-Bromo-5'-nitro-1H,1'H-[2,3']biindolylidene-3...)
Affinity DataIC50: 50nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50304113(N-((Z)-5-Bromo-3,2'-dioxo-1,3,1',2'-tetrahydro-[2,...)
Affinity DataIC50: 110nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50423711(CHEMBL594403)
Affinity DataIC50: 120nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50304112((Z)-5'-Amino-1H,1'H-[2,3']biindolylidene-3,2'-dion...)
Affinity DataIC50: 150nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50304114(N-{3-[Hydroxyimino]-2'-oxo-1,3,1',2'-tetrahydro-[2...)
Affinity DataIC50: 160nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50423712(CHEMBL593968)
Affinity DataIC50: 200nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50423713(CHEMBL606982)
Affinity DataIC50: 300nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50304119((Z)-5'-Amino-5-bromo-1H,1'H-[2,3']biindolylidene-3...)
Affinity DataIC50: 550nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50304110((Z)-5'-Amino-1H,1'H-[2,3']biindolylidene-3,2'-dion...)
Affinity DataIC50: 590nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50304123((Z)-5'-Amino-5-bromo-1H,1'H-[2,3']biindolylidene-3...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304109(5'-Nitro-1H,1'H-[2,3']biindolylidene-3,2'-dione 3-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304110((Z)-5'-Amino-1H,1'H-[2,3']biindolylidene-3,2'-dion...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304111(N-((Z)-3,2'-Dioxo-1,3,1',2'-tetrahydro-[2,3']biind...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50304124(N-{(Z)-5-Bromo-3-[(E)-hydroxyimino]-2'-oxo-1,3,1',...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50423714((2''Z)-6-Aminoindirubin | CHEMBL609580)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304112((Z)-5'-Amino-1H,1'H-[2,3']biindolylidene-3,2'-dion...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304113(N-((Z)-5-Bromo-3,2'-dioxo-1,3,1',2'-tetrahydro-[2,...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50423716(CHEMBL606865)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304123((Z)-5'-Amino-5-bromo-1H,1'H-[2,3']biindolylidene-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50423715((2''Z)-6-Nitroindirubin | CHEMBL593700)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50304122((Z)-5,7'-Dibromo-5'-nitro-1H,1'H-[2,3']biindolylid...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50304120((Z)-7'-Bromo-5'-nitro-1H,1'H-[2,3']biindolylidene-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50304118((Z)-5-Bromo-5'-nitro-1H,1'H-[2,3']biindolylidene-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50304117((2'Z)-5'-7-Dibromo-5-nitroindirubin | CHEMBL606814)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50304115((2'Z)-7-Bromo-5-nitroindirubin | CHEMBL605926)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304115((2'Z)-7-Bromo-5-nitroindirubin | CHEMBL605926)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304116((Z)-5'-Nitro-1H,1'H-[2,3']biindolylidene-3,2'-dion...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304117((2'Z)-5'-7-Dibromo-5-nitroindirubin | CHEMBL606814)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304118((Z)-5-Bromo-5'-nitro-1H,1'H-[2,3']biindolylidene-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304119((Z)-5'-Amino-5-bromo-1H,1'H-[2,3']biindolylidene-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304120((Z)-7'-Bromo-5'-nitro-1H,1'H-[2,3']biindolylidene-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304121((Z)-5-Bromo-5'-nitro-1H,1'H-[2,3']biindolylidene-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304122((Z)-5,7'-Dibromo-5'-nitro-1H,1'H-[2,3']biindolylid...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304124(N-{(Z)-5-Bromo-3-[(E)-hydroxyimino]-2'-oxo-1,3,1',...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304114(N-{3-[Hydroxyimino]-2'-oxo-1,3,1',2'-tetrahydro-[2...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
La Rochelle University

Curated by ChEMBL
LigandPNGBDBM50304116((Z)-5'-Nitro-1H,1'H-[2,3']biindolylidene-3,2'-dion...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed