Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50033483
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249758BDBM50249758(2-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridy...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human NPYY5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249833BDBM50249833(6-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoro-3-pyridy...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346211BDBM50346211(6-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346228BDBM50346228(1-(Difluoromethyl)-5-[(4S,5S)-4-(4-fluorophenyl)-4...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346229BDBM50346229(5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346225BDBM50346225(1-Ethyl-5-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluorop...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346221BDBM50346221(3-Chloro-5-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoro...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346227BDBM50346227(5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346222BDBM50346222(5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataKi:  3.80nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346217BDBM50346217(5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346226BDBM50346226(5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346223BDBM50346223(5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346231BDBM50346231(1-Ethyl-5-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluorop...)
Affinity DataKi:  6.60nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346214BDBM50346214(3-Fluoro-6-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoro...)
Affinity DataKi:  6.90nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346230BDBM50346230(1-Ethoxy-5-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoro...)
Affinity DataKi:  7.30nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346233BDBM50346233(5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataKi:  7.40nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346232BDBM50346232(1-(Difluoromethyl)-5-[(4S,5S)-4-(4-fluorophenyl)-4...)
Affinity DataKi:  8.5nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346212BDBM50346212(6-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataKi:  8.60nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346215BDBM50346215(3-Chloro-6-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoro...)
Affinity DataKi:  8.60nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346228BDBM50346228(1-(Difluoromethyl)-5-[(4S,5S)-4-(4-fluorophenyl)-4...)
Affinity DataIC50: 8.70nMAssay Description:Antagonist activity at human recombinant NPYY5 receptor expressed in mouse LMtk- cells co-expressing Gqi5 assessed as inhibition of NPY-induced calci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346228BDBM50346228(1-(Difluoromethyl)-5-[(4S,5S)-4-(4-fluorophenyl)-4...)
Affinity DataIC50: 10nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346229BDBM50346229(5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataIC50: 10nMAssay Description:Displacement of [35S]N-[(4R)-10-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,40-piperidin]-6-yl]meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346220BDBM50346220(3-Fluoro-5-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoro...)
Affinity DataKi:  11nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346224BDBM50346224(5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346229BDBM50346229(5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataIC50: 15.7nMAssay Description:Antagonist activity at human recombinant NPYY5 receptor expressed in mouse LMtk- cells co-expressing Gqi5 assessed as inhibition of NPY-induced calci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346213BDBM50346213(6-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataKi:  28nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346210BDBM50346210(4-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataKi:  42nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346216BDBM50346216(6-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataKi:  350nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346234BDBM50346234(3-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataKi:  600nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346218BDBM50346218(5-[(4S,5S)-4-(4-Fluorophenyl)-4-(6-fluoropyridin-3...)
Affinity DataKi:  630nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346219BDBM50346219(6-Fluoro-5-[(4S,5S)-4-(4-fluorophenyl)-4-(6-fluoro...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346228BDBM50346228(1-(Difluoromethyl)-5-[(4S,5S)-4-(4-fluorophenyl)-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human NPYY1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346228BDBM50346228(1-(Difluoromethyl)-5-[(4S,5S)-4-(4-fluorophenyl)-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human NPYY2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 4(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346228BDBM50346228(1-(Difluoromethyl)-5-[(4S,5S)-4-(4-fluorophenyl)-4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human NPYY4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed