Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50030490
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50296974(4-((1H-imidazol-1-yl)methyl)phenyl 4-iodobenzenesu...)
Affinity DataIC50: 65.1nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetAromatase(Human)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50188097(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)
Affinity DataIC50: 70nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50296973(4-((1H-imidazol-1-yl)methyl)phenyl 4-bromobenzenes...)
Affinity DataIC50: 70.4nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50296970(4-((1H-imidazol-1-yl)methyl)phenyl 4-nitrobenzenes...)
Affinity DataIC50: 85nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50296972(4-((1H-imidazol-1-yl)methyl)phenyl 4-chlorobenzene...)
Affinity DataIC50: 98.7nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50296975(4-((1H-imidazol-1-yl)methyl)phenyl 4-methoxybenzen...)
Affinity DataIC50: 101nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetAromatase(Human)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50188093(1-(4-Nitro-benzyl)-1H-imidazole | 1-(4-nitrobenzyl...)
Affinity DataIC50: 130nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50296971(4-((1H-imidazol-1-yl)methyl)phenyl 4-fluorobenzene...)
Affinity DataIC50: 210nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50296969(4-((1H-imidazol-1-yl)methyl)phenyl 4-methylbenzene...)
Affinity DataIC50: 230nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50296976(4-((1H-imidazol-1-yl)methyl)phenyl 4-(trifluoromet...)
Affinity DataIC50: 291nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetAromatase(Human)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50188085(1-(4-Fluorobenzyl)-1H-imidazole | CHEMBL377770)
Affinity DataIC50: 880nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetAromatase(Human)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50008733(4-((1H-imidazol-1-yl)methyl)benzonitrile | 4-Imida...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50188092(4-iodobenzyl imidazole | 1-(4-iodobenzyl)-1H-imida...)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataIC50: 3.76E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50296973(4-((1H-imidazol-1-yl)methyl)phenyl 4-bromobenzenes...)
Affinity DataIC50: 4.84E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50296975(4-((1H-imidazol-1-yl)methyl)phenyl 4-methoxybenzen...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50296972(4-((1H-imidazol-1-yl)methyl)phenyl 4-chlorobenzene...)
Affinity DataIC50: 6.85E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50296970(4-((1H-imidazol-1-yl)methyl)phenyl 4-nitrobenzenes...)
Affinity DataIC50: 6.88E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50296974(4-((1H-imidazol-1-yl)methyl)phenyl 4-iodobenzenesu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50188092(4-iodobenzyl imidazole | 1-(4-iodobenzyl)-1H-imida...)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50296971(4-((1H-imidazol-1-yl)methyl)phenyl 4-fluorobenzene...)
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetAromatase(Human)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50188087(1-(4-methyl-benzyl)-1H-imidazole | 1-(4-methylbenz...)
Affinity DataIC50: 2.45E+4nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50296969(4-((1H-imidazol-1-yl)methyl)phenyl 4-methylbenzene...)
Affinity DataIC50: 2.52E+4nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM50296976(4-((1H-imidazol-1-yl)methyl)phenyl 4-(trifluoromet...)
Affinity DataIC50: 6.49E+4nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetAromatase(Human)
University of The West of Scotland

Curated by ChEMBL
LigandPNGBDBM4339(2-[(3,4-dihydroxyphenyl)methylidene]propanedinitri...)
Affinity DataIC50: 7.06E+4nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed