Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50030478
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296807(5-ethyl-2-(2-(4-methylpiperazin-1-yl)pyridin-3-yl)...)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296805(5-ethyl-2-(2-(4-(1-methylpiperidin-4-yl)piperazin-...)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296806(1-(3-(5-ethyl-4-oxo-4H-benzo[d][1,3]oxazin-2-yl)py...)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296826(5-ethyl-2-(2-(4-(2-hydroxyethyl)piperazin-1-yl)pyr...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296830(5-ethyl-7-methoxy-2-(2-(4-(2-methoxyethyl)piperazi...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296834((R)-1-(3-(5-ethyl-7-methoxy-4-oxo-4H-benzo[d][1,3]...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296804(5-ethyl-7-methoxy-2-(2-(4-methylpiperazin-1-yl)pyr...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296824(2-(2-(4-(2-(dimethylamino)ethyl)piperazin-1-yl)pyr...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296828(5-ethyl-2-(2-(4-isobutylpiperazin-1-yl)pyridin-3-y...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296827(5-ethyl-7-methoxy-2-(2-(4-(2-morpholinoethyl)piper...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296835(2-(4-(3-(5-ethyl-7-methoxy-4-oxo-4H-benzo[d][1,3]o...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296825(3-(4-(3-(5-ethyl-7-methoxy-4-oxo-4H-benzo[d][1,3]o...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296833((S)-1-(3-(5-ethyl-7-methoxy-4-oxo-4H-benzo[d][1,3]...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296829(2-(2-(4-butylpiperazin-1-yl)pyridin-3-yl)-5-ethyl-...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296802(5-ethyl-7-methoxy-2-(2-(4-(1-methylpiperidin-4-yl)...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296803(1-(3-(5-ethyl-7-methoxy-4-oxo-4H-benzo[d][1,3]oxaz...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296831(2-(2-(4-(cyclopropylmethyl)piperazin-1-yl)pyridin-...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296832(2-(2-(4-cyclopentylpiperazin-1-yl)pyridin-3-yl)-5-...)
Affinity DataIC50: 34nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296823(5-methyl-2-(2-phenoxypyridin-3-yl)-4H-benzo[d][1,3...)
Affinity DataIC50: 61nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296811(2-(2-(1H-imidazol-1-yl)pyridin-3-yl)-5-methyl-4H-b...)
Affinity DataIC50: 64nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296797(7-methoxy-2-(2-(4-(1-methylpiperidin-4-yl)piperazi...)
Affinity DataIC50: 71nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296808(5-methyl-2-(2-(4-(1-methylpiperidin-4-yl)piperazin...)
Affinity DataIC50: 74nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296809(1-(3-(5-methyl-4-oxo-4H-benzo[d][1,3]oxazin-2-yl)p...)
Affinity DataIC50: 79nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296819(2-(2-methoxypyridin-3-yl)-5-methyl-4H-benzo[d][1,3...)
Affinity DataIC50: 85nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296818(5-methyl-2-(2-methylpyridin-3-yl)-4H-benzo[d][1,3]...)
Affinity DataIC50: 87nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296810(5-methyl-2-(2-(4-methylpiperazin-1-yl)pyridin-3-yl...)
Affinity DataIC50: 93nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296812(2-(2-((2-(dimethylamino)ethyl)(methyl)amino)pyridi...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296840(5-cyclopropyl-7-methoxy-2-(2-(4-(1-methylpiperidin...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296793(5-cyclopropyl-7-methoxy-2-(2-(4-methylpiperazin-1-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296792(1-(3-(5-cyclopropyl-7-methoxy-4-oxo-4H-benzo[d][1,...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296794(5-isopropyl-7-methoxy-2-(2-(4-(1-methylpiperidin-4...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296839(5-cyclobutyl-7-methoxy-2-(2-(4-methylpiperazin-1-y...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296816(5-chloro-2-(2-phenoxypyridin-3-yl)-4H-benzo[d][1,3...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296822(5-methyl-2-(2-phenoxyphenyl)-4H-benzo[d][1,3]oxazi...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296798(1-(3-(7-methoxy-4-oxo-5-propyl-4H-benzo[d][1,3]oxa...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296796(5-isopropyl-7-methoxy-2-(2-(4-methylpiperazin-1-yl...)
Affinity DataIC50: 210nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296799(7-methoxy-2-(2-(4-methylpiperazin-1-yl)pyridin-3-y...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296795(1-(3-(5-isopropyl-7-methoxy-4-oxo-4H-benzo[d][1,3]...)
Affinity DataIC50: 330nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296815(5-methoxy-2-(2-phenoxypyridin-3-yl)-4H-benzo[d][1,...)
Affinity DataIC50: 390nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296817(5-methyl-2-(6-methylpyridin-3-yl)-4H-benzo[d][1,3]...)
Affinity DataIC50: 710nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296837(5-cyclobutyl-7-methoxy-2-(2-(4-(1-methylpiperidin-...)
Affinity DataIC50: 850nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296820(5-methyl-2-(pyridin-3-yl)-4H-benzo[d][1,3]oxazin-4...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296838(1-(3-(5-cyclobutyl-7-methoxy-4-oxo-4H-benzo[d][1,3...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296800(7-(dimethylamino)-5-ethyl-2-(2-(4-(1-methylpiperid...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296801(7-(dimethylamino)-5-ethyl-2-(2-(4-methylpiperazin-...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296814(5-methyl-2-(2-(2-morpholinoethylamino)pyridin-3-yl...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296813(2-(2-(2-(dimethylamino)ethylamino)pyridin-3-yl)-5-...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296821(2-(2-phenoxypyridin-3-yl)-4H-benzo[d][1,3]oxazin-4...)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Activx Biosciences

Curated by ChEMBL
LigandPNGBDBM50296836(5-tert-butyl-7-methoxy-2-(2-(4-methylpiperazin-1-y...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human sputum neutrophil elastase by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed