Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50032045
TargetEstrogen receptor(Human)
Institut FüR Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50323701(2-(Trifluoroacetyl)-1,2,3,4-tetrahydro-6-isoquinol...)
Affinity DataEC50:  275nMAssay Description:Binding affinity to human ERalpha ligand binding domain expressed in Escherichia coli BL21(DE3) cells assessed as recruitment of fluorescently labele...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Institut FüR Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50323701(2-(Trifluoroacetyl)-1,2,3,4-tetrahydro-6-isoquinol...)
Affinity DataEC50:  4.60E+3nMAssay Description:Binding affinity to human ERbeta ligand binding domain expressed in Escherichia coli BL21(DE3) cells assessed as recruitment of fluorescently labeled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Institut FüR Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50323700(N-(2-(dimethylamino)ethyl)-4-((naphthalen-2-yloxy)...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of LOX5 in human whole blood assessed as inhibition of conversion of arachidonic acid to leukotrieneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Institut FüR Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50323699(2-(benzyloxy)naphthalene | 2-Benzyloxy-naphthalene...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of LOX5 in human whole blood assessed as inhibition of conversion of arachidonic acid to leukotrieneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Institut FüR Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50323701(2-(Trifluoroacetyl)-1,2,3,4-tetrahydro-6-isoquinol...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]estradiol from human ERalpha ligand binding domain expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed