Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 4729
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM10881(CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...)
Affinity DataKi:  2.10nM ΔG°:  -49.5kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  2.5nM ΔG°:  -49.1kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  12nM ΔG°:  -45.2kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM10881(CHEMBL288100 | cid_4100 | N-[(2Z)-3-methyl-5-sulfa...)
Affinity DataKi:  14nM ΔG°:  -44.8kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM50025093(p-Halide-sulfanilamide derivative, 2 | P-Chloroben...)
Affinity DataKi:  17.5nM ΔG°:  -44.3kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM10883(Dichlorophenamide, DCP | CHEMBL17 | Sulfonamide, 4...)
Affinity DataKi:  26.5nM ΔG°:  -43.2kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM33269(CHEMBL277836 | p-Phenyldiazenyl derivative, 4 | ci...)
Affinity DataKi:  30nM ΔG°:  -42.9kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM10888(Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...)
Affinity DataKi:  35nM ΔG°:  -42.6kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM10883(Dichlorophenamide, DCP | CHEMBL17 | Sulfonamide, 4...)
Affinity DataKi:  38nM ΔG°:  -42.4kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM33266(p-Phenyldiazenyl derivative, 5 | CHEMBL379206 | az...)
Affinity DataKi:  46nM ΔG°:  -41.9kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM50025093(p-Halide-sulfanilamide derivative, 2 | P-Chloroben...)
Affinity DataKi:  53nM ΔG°:  -41.5kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM81918(p-Halide-sulfanilamide derivative, 2a)
Affinity DataKi:  68nM ΔG°:  -40.9kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM81919(p-Halide-sulfanilamide derivative, 3)
Affinity DataKi:  70nM ΔG°:  -40.8kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM81918(p-Halide-sulfanilamide derivative, 2a)
Affinity DataKi:  81nM ΔG°:  -40.5kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM81919(p-Halide-sulfanilamide derivative, 3)
Affinity DataKi:  81nM ΔG°:  -40.5kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM81920(p-Hydroxy-benzene derivative, 3a)
Affinity DataKi:  88nM ΔG°:  -40.3kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM81920(p-Hydroxy-benzene derivative, 3a)
Affinity DataKi:  89nM ΔG°:  -40.2kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM10888(Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...)
Affinity DataKi:  117nM ΔG°:  -39.6kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM81923(p-Phenyldiazenyl derivative, 8)
Affinity DataKi:  277nM ΔG°:  -37.4kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM81922(p-Phenyldiazenyl derivative, 7)
Affinity DataKi:  312nM ΔG°:  -37.1kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM33269(CHEMBL277836 | p-Phenyldiazenyl derivative, 4 | ci...)
Affinity DataKi:  638nM ΔG°:  -35.4kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM33266(p-Phenyldiazenyl derivative, 5 | CHEMBL379206 | az...)
Affinity DataKi:  665nM ΔG°:  -35.3kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM81923(p-Phenyldiazenyl derivative, 8)
Affinity DataKi:  706nM ΔG°:  -35.1kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM81922(p-Phenyldiazenyl derivative, 7)
Affinity DataKi:  752nM ΔG°:  -35.0kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM81921(p-Phenyldiazenyl derivative, 6)
Affinity DataKi:  863nM ΔG°:  -34.6kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM81921(p-Phenyldiazenyl derivative, 6)
Affinity DataKi:  4.20E+3nM ΔG°:  -30.7kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed