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Found
6
Enz. Inhib. hit(s) with all data for entry = 50030446
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50296256
(7-(6-methoxypyridin-3-yl)-3-(2-morpholinoethylamin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.0700nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/26/2010
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50296257
(7-(6-methoxypyridin-3-yl)-3-(2-morpholinoethylamin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.340nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/26/2010
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50296253
(7-(6-methoxypyridin-3-yl)-3-(2-morpholinoethylamin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.900nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/26/2010
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50296254
(2-(6-methoxypyridin-3-yl)-6-(2-morpholinoethylamin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.20nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/26/2010
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50296255
(7-(6-methoxypyridin-3-yl)-3-(2-morpholinoethylamin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.20nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/26/2010
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50296252
(6-(6-methoxypyridin-3-yl)-2-(2-morpholinoethylamin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.90nM
Assay Description:
Inhibition of PDE5
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
8/26/2010
Entry Details
Article
Copy Entry DOI
PubMed
Copy Rxn URL