Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50030443
TargetTyrosinase(Mouse)
National Institute of Advanced Industrial Science and Technology

Curated by ChEMBL
LigandPNGBDBM50296247(3-(3,4-Dihydroxyphenyl)-N-[2-(5-hydroxyindol-3-yl)...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosinase(Mouse)
National Institute of Advanced Industrial Science and Technology

Curated by ChEMBL
LigandPNGBDBM50296244(2,4-dihydroxy-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosinase(Mouse)
National Institute of Advanced Industrial Science and Technology

Curated by ChEMBL
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosinase(Mouse)
National Institute of Advanced Industrial Science and Technology

Curated by ChEMBL
LigandPNGBDBM32212(cid_16054 | 1H-indol-5-ol)
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosinase(Mouse)
National Institute of Advanced Industrial Science and Technology

Curated by ChEMBL
LigandPNGBDBM50296245(3,4-Dihydroxy-N-[2-(5-hydroxyindol-3-yl)ethyl]benz...)
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosinase(Mouse)
National Institute of Advanced Industrial Science and Technology

Curated by ChEMBL
LigandPNGBDBM50296243(4-hydroxy-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-3-m...)
Affinity DataIC50: 2.11E+5nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosinase(Mouse)
National Institute of Advanced Industrial Science and Technology

Curated by ChEMBL
LigandPNGBDBM50296246(N-Feruloylserotonin | CHEMBL564482)
Affinity DataIC50: 2.16E+5nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosinase(Mouse)
National Institute of Advanced Industrial Science and Technology

Curated by ChEMBL
LigandPNGBDBM50296242(4-hydroxy-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)benz...)
Affinity DataIC50: 2.33E+5nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosinase(Mouse)
National Institute of Advanced Industrial Science and Technology

Curated by ChEMBL
LigandPNGBDBM29612(N-Acetyltryptamine,5-Hydroxy | CHEMBL33103 | Norme...)
Affinity DataIC50: 3.11E+5nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosinase(Mouse)
National Institute of Advanced Industrial Science and Technology

Curated by ChEMBL
LigandPNGBDBM50296248(N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)benzamide | CH...)
Affinity DataIC50: 3.33E+5nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosinase(Mouse)
National Institute of Advanced Industrial Science and Technology

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataIC50: 5.50E+5nMAssay Description:Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosinase(Mouse)
National Institute of Advanced Industrial Science and Technology

Curated by ChEMBL
LigandPNGBDBM50414514(PROTOCATECHUAMIDE)
Affinity DataKi:  3.70E+3nMAssay Description:Apparent noncompetitive inhibition of catecholase activity of tyrosinase in mouse B16 cells by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosinase(Mouse)
National Institute of Advanced Industrial Science and Technology

Curated by ChEMBL
LigandPNGBDBM50296245(3,4-Dihydroxy-N-[2-(5-hydroxyindol-3-yl)ethyl]benz...)
Affinity DataKi:  6.40E+4nMAssay Description:Apparent noncompetitive inhibition of catecholase activity of tyrosinase in mouse B16 cells by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosinase(Mouse)
National Institute of Advanced Industrial Science and Technology

Curated by ChEMBL
LigandPNGBDBM29612(N-Acetyltryptamine,5-Hydroxy | CHEMBL33103 | Norme...)
Affinity DataKi:  2.40E+5nMAssay Description:Apparent noncompetitive inhibition of catecholase activity of tyrosinase in mouse B16 cells by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed