Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50030441
TargetMatrix metalloproteinase-14(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296234((2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)ch...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant MT1-MMP expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296238((2S,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)ch...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human recombinant MT1-MMP expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296237(3,5-Dihydroxy-4-methoxy-benzoic acid (2R,3R)-2-(3,...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human recombinant MT1-MMP expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296238((2S,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)ch...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human recombinant MMP2 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human recombinant MT1-MMP expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296234((2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)ch...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human recombinant MMP2 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of human recombinant MMP2 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296239((2S,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)ch...)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of human recombinant MT1-MMP expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296235((-)-Epigallocatechin-3-(4''-O-methyl)gallate | (2R...)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of human recombinant MT1-MMP expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296236(3,4-Dihydroxy-5-methoxy-benzoic acid (2R,3R)-2-(3,...)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of human recombinant MT1-MMP expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296235((-)-Epigallocatechin-3-(4''-O-methyl)gallate | (2R...)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of human recombinant MMP2 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296239((2S,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)ch...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant MMP2 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296234((2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)ch...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant MMP7 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296238((2S,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)ch...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant MMP7 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of human recombinant MMP7 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296241((2R,3S)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxychrom...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human recombinant MMP2 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296240((2R,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychrom...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human recombinant MMP2 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296239((2S,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)ch...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human recombinant MMP7 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296237(3,5-Dihydroxy-4-methoxy-benzoic acid (2R,3R)-2-(3,...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human recombinant MMP2 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296240((2R,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychrom...)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of human recombinant MT1-MMP expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296235((-)-Epigallocatechin-3-(4''-O-methyl)gallate | (2R...)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of human recombinant MMP7 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296236(3,4-Dihydroxy-5-methoxy-benzoic acid (2R,3R)-2-(3,...)
Affinity DataIC50: 8.80E+4nMAssay Description:Inhibition of human recombinant MMP2 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296237(3,5-Dihydroxy-4-methoxy-benzoic acid (2R,3R)-2-(3,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP7 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296236(3,4-Dihydroxy-5-methoxy-benzoic acid (2R,3R)-2-(3,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP7 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296241((2R,3S)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxychrom...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MT1-MMP expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296240((2R,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychrom...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP7 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296241((2R,3S)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxychrom...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP7 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed