Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50028836
TargetPeroxisome proliferator-activated receptor alpha(Dog)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267991((R)-2-(3-(3-(4-methoxybenzoyl)-2-methyl-6-(trifluo...)
Affinity DataEC50:  370nMAssay Description:Agonist activity at dog PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267991((R)-2-(3-(3-(4-methoxybenzoyl)-2-methyl-6-(trifluo...)
Affinity DataEC50:  240nMAssay Description:Agonist activity at mouse PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157917((S)-2-{3-[1-(4-Methoxy-benzoyl)-2-methyl-5-trifluo...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human recombinant PPARgamma expressed in COS1 cells co-expressing GAL4 assessed as transcriptional activity after 48 hrs by lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166298((S)-2-{4-Chloro-3-[1-(6-chloro-benzo[d]isoxazol-3-...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human recombinant PPARgamma expressed in COS1 cells co-expressing GAL4 assessed as transcriptional activity after 48 hrs by lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50268271((S)-2-(3-((3-(4-methoxybenzoyl)-2-methyl-6-(triflu...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human recombinant PPARgamma expressed in COS1 cells co-expressing GAL4 assessed as transcriptional activity after 48 hrs by lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267989((2S)-2-(4-chloro-3-((3-(6-methoxybenzo[d]isoxazol-...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human recombinant PPARgamma expressed in COS1 cells co-expressing GAL4 assessed as transcriptional activity after 48 hrs by lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267990((S)-2-(2-chloro-5-((3-(4-chlorophenoxy)-2-methyl-6...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human recombinant PPARgamma expressed in COS1 cells co-expressing GAL4 assessed as transcriptional activity after 48 hrs by lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267991((R)-2-(3-(3-(4-methoxybenzoyl)-2-methyl-6-(trifluo...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human recombinant PPARgamma expressed in COS1 cells co-expressing GAL4 assessed as transcriptional activity after 48 hrs by lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human recombinant PPARgamma expressed in COS1 cells co-expressing GAL4 assessed as transcriptional activity after 48 hrs by lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157917((S)-2-{3-[1-(4-Methoxy-benzoyl)-2-methyl-5-trifluo...)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H2]nTZD3 from human recombinant GST-fused PPARgamma expressed in Escherichia coli by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50268271((S)-2-(3-((3-(4-methoxybenzoyl)-2-methyl-6-(triflu...)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H2]nTZD3 from human recombinant GST-fused PPARgamma expressed in Escherichia coli by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267990((S)-2-(2-chloro-5-((3-(4-chlorophenoxy)-2-methyl-6...)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H2]nTZD3 from human recombinant GST-fused PPARgamma expressed in Escherichia coli by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267989((2S)-2-(4-chloro-3-((3-(6-methoxybenzo[d]isoxazol-...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H2]nTZD3 from human recombinant GST-fused PPARgamma expressed in Escherichia coli by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166298((S)-2-{4-Chloro-3-[1-(6-chloro-benzo[d]isoxazol-3-...)
Affinity DataIC50: 6nMAssay Description:Displacement of [3H2]nTZD3 from human recombinant GST-fused PPARgamma expressed in Escherichia coli by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267991((R)-2-(3-(3-(4-methoxybenzoyl)-2-methyl-6-(trifluo...)
Affinity DataIC50: 9nMAssay Description:Displacement of [3H2]nTZD3 from human recombinant GST-fused PPARgamma expressed in Escherichia coli by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataIC50: 200nMAssay Description:Displacement of [3H2]nTZD3 from human recombinant GST-fused PPARgamma expressed in Escherichia coli by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267991((R)-2-(3-(3-(4-methoxybenzoyl)-2-methyl-6-(trifluo...)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H2]nTZD3 from human recombinant GST-fused PPARalpha expressed in Escherichia coli by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H2]nTZD3 from human recombinant GST-fused PPARalpha expressed in Escherichia coli by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed