Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50030435
TargetAcetylcholinesterase(Human)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296117(2-(6-(ethyl((R)-1-(2-methoxyphenyl)ethyl)amino)hex...)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of human recombinant AChE preincubated 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296119(2,5-bis(6-(ethyl((R)-1-(2-methoxyphenyl)ethyl)amin...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human recombinant AChE preincubated 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50231951(2,5-bis(6-((2-methoxybenzyl)(ethyl)amino)hexylamin...)
Affinity DataIC50: 1.55nMAssay Description:Inhibition of human recombinant AChE preincubated 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296118(2,5-bis(6-(ethyl((S)-1-(2-methoxyphenyl)ethyl)amin...)
Affinity DataIC50: 4.03nMAssay Description:Inhibition of human recombinant AChE preincubated 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296118(2,5-bis(6-(ethyl((S)-1-(2-methoxyphenyl)ethyl)amin...)
Affinity DataIC50: 958nMAssay Description:Inhibition of human recombinant BchE preincubated 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296117(2-(6-(ethyl((R)-1-(2-methoxyphenyl)ethyl)amino)hex...)
Affinity DataIC50: 982nMAssay Description:Inhibition of human recombinant BchE preincubated 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50231951(2,5-bis(6-((2-methoxybenzyl)(ethyl)amino)hexylamin...)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of human recombinant BchE preincubated 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296119(2,5-bis(6-(ethyl((R)-1-(2-methoxyphenyl)ethyl)amin...)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of human recombinant BchE preincubated 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296118(2,5-bis(6-(ethyl((S)-1-(2-methoxyphenyl)ethyl)amin...)
Affinity DataIC50: 7.91E+3nMAssay Description:Inhibition of human AChE-induced amyloid beta (1-40) aggregation by thioflavin T fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296119(2,5-bis(6-(ethyl((R)-1-(2-methoxyphenyl)ethyl)amin...)
Affinity DataIC50: 9.34E+3nMAssay Description:Inhibition of human AChE-induced amyloid beta (1-40) aggregation by thioflavin T fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296117(2-(6-(ethyl((R)-1-(2-methoxyphenyl)ethyl)amino)hex...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human AChE-induced amyloid beta (1-40) aggregation by thioflavin T fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50231951(2,5-bis(6-((2-methoxybenzyl)(ethyl)amino)hexylamin...)
Affinity DataIC50: 2.83E+4nMAssay Description:Inhibition of human AChE-induced amyloid beta (1-40) aggregation by thioflavin T fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed