Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50030418
TargetMelatonin receptor type 1A(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50295869(N-[2-(8-Methoxy-2-methyl-1,2,3,4-tetrahydropyrazin...)
Affinity DataIC50: 3.14nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50295871(N-[2-(5-Methoxy-2-{[(4-methoxyphenyl)(methyl)amino...)
Affinity DataKi:  8nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cells by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50295871(N-[2-(5-Methoxy-2-{[(4-methoxyphenyl)(methyl)amino...)
Affinity DataKi:  9nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cells by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50295870(N-{2-(5-Methoxy-2-({[methyl[4-(trifluoromethyl)phe...)
Affinity DataKi:  63nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cells by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50295870(N-{2-(5-Methoxy-2-({[methyl[4-(trifluoromethyl)phe...)
Affinity DataKi:  111nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cells by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50273283(N-[2-(13a,14-Dihydro-6H,13H-pyrazino[1,2-a;4,5-a']...)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cells by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50273283(N-[2-(13a,14-Dihydro-6H,13H-pyrazino[1,2-a;4,5-a']...)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cells by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed