Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50030574
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50298278(N-(4-Amino-2,6-diisopropylphenyl)-N'-{[1-[3-(3-hyd...)
Affinity DataIC50: 4nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50298281(CHEMBL1091036 | N-(4-Amino-2,6-diisopropylphenyl)-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50175765(CHEMBL454397 | CHEMBL539597 | CHEMBL573970 | 1-(4-...)
Affinity DataIC50: 31nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50276562(CHEMBL574414 | CHEMBL449832 | 1-(4-amino-2,6-diiso...)
Affinity DataIC50: 32nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50276483(1-(2,6-diisopropylphenyl)-3-((4-(3-methoxyphenyl)-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50276487(CHEMBL576152 | CHEMBL500498 | 1-(4-amino-2,6-diiso...)
Affinity DataIC50: 37nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50298286(N-(4-Amino-2,6-diisopropylphenyl)-N'-{[1-(2-isopro...)
Affinity DataIC50: 37nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50276485(CHEMBL574486 | CHEMBL449977 | 1-(4-amino-2,6-diiso...)
Affinity DataIC50: 40nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50276488(CHEMBL442567 | CHEMBL572410 | 1-(4-amino-2,6-diiso...)
Affinity DataIC50: 48nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50276565(CHEMBL503766 | 1-(4-amino-2,6-diisopropylphenyl)-3...)
Affinity DataIC50: 48nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50298279(N-(4-Amino-2,6-diisopropylphenyl)-N'-{[4-[3-(3-hyd...)
Affinity DataIC50: 62nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50276564(CHEMBL509834 | 1-(4-amino-2,6-diisopropylphenyl)-3...)
Affinity DataIC50: 68nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50276491(CHEMBL578002 | CHEMBL448407 | 1-(4-amino-2,6-diiso...)
Affinity DataIC50: 82nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50298282(N-(4-Amino-2,6-diisopropylphenyl)-N'-{[1-[2-(2-hyd...)
Affinity DataIC50: 96nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50276489(CHEMBL574940 | CHEMBL364823 | 1-(4-amino-2,6-diiso...)
Affinity DataIC50: 142nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50298284(N-(4-Amino-2,6-diisopropylphenyl)-N'-{[1-[2-(3-ami...)
Affinity DataIC50: 195nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50298283(N-(4-Amino-2,6-diisopropylphenyl)-N'-{[1-{2-(3-(di...)
Affinity DataIC50: 239nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50069900(CHEMBL101309 | [2-(2,4,6-Triisopropyl-phenyl)-acet...)
Affinity DataIC50: 479nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50298280(N-(4-Amino-2,6-diisopropylphenyl)-N'-{[4-(3-hydrox...)
Affinity DataIC50: 797nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50298296(N-(4-Amino-2,6-diisopropylphenyl)-N'-{[4-(3-methox...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50298295(N-(4-Amino-2,6-diisopropylphenyl)-N'-{[4-(3-methox...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50298298(N-(4-Amino-2,6-diisopropylphenyl)-N'-{[4-(3-methox...)
Affinity DataIC50: 4.66E+5nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50298297(N-(4-Amino-2,6-diisopropylphenyl)-N'-{[4-(3-methox...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of ACAT in rat macrophages assessed as incorporation of extracellular [3H]-oleic acid-BSA complex into the intracellular cholesteryl ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed