Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50028762
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 4.08E+3nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 3.99E+3nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 1.93E+3nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 5.38E+3nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 3.96E+3nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 7.15E+3nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 1.70E+3nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 6.38E+3nMAssay Description:Activation of human muscarinic M3 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 1.16E+3nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 5.88E+3nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 3.19E+3nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 6.21E+3nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 4.09E+3nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 8.55E+3nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 7.13E+3nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 5.18E+3nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 3.20E+3nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 2.11E+3nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 7.09E+3nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 1.85E+3nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 4.07E+3nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 7.14E+3nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 4.66E+3nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 1.86E+3nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 3.26E+3nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 3.28E+3nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of human muscarinic M3 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 2.84E+3nMAssay Description:Activation of rat muscarinic M2 receptor expressed in CHO cells co-expressing chimeric Gqi5 protein assessed as potentiation of acetylcholine-induced...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 2.22E+3nMAssay Description:Activation of human muscarinic M3 receptor expressed in CHO cells coexpressing Gq protein assessed as potentiation of acetylcholine-induced intracell...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of rat muscarinic M4 receptor expressed in CHO cells coexpressing chimeric Gqi5 protein assessed as potentiation of acetylcholine-induced ...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Rat)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 6.04E+3nMAssay Description:Activation of rat muscarinic M1 receptor expressed in CHO cells co-expressing Gq protein assessed as potentiation of acetylcholine-induced intracellu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataKi: 159nMAssay Description:Displacement of [3H]NMS from human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein by scintillation counting in presence of ace...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataKi: 1.61E+3nMAssay Description:Displacement of [3H]NMS from human muscarinic M5 receptor expressed in CHO cells coexpressing Gq protein by scintillation countingMore data for this Ligand-Target Pair


















