Compile Data Set for Download or QSAR
Report error Found 71 Enz. Inhib. hit(s) with all data for entry = 3304
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31164(naphthyridinone analog.,18)
Affinity DataKd:  2nMAssay Description:Binding affinity and kinetics were measured using biotinylated recombinant human DAAO bound to a Neutravidin surface in a Biacore binding assay. A cu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31161(3-hydroxyquinolin-2(1H)-one, 15)
Affinity DataKd:  25nMAssay Description:Binding affinity and kinetics were measured using biotinylated recombinant human DAAO bound to a Neutravidin surface in a Biacore binding assay. A cu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31152(3-hydroxyquinolin-2(1H)-one, 6)
Affinity DataKd:  18nMAssay Description:Binding affinity and kinetics were measured using biotinylated recombinant human DAAO bound to a Neutravidin surface in a Biacore binding assay. A cu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31151(3-hydroxyquinolin-2(1H)-one, 5)
Affinity DataKd:  17nMAssay Description:Binding affinity and kinetics were measured using biotinylated recombinant human DAAO bound to a Neutravidin surface in a Biacore binding assay. A cu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31150(3-hydroxyquinolin-2(1H)-one, 4)
Affinity DataKd:  38nMAssay Description:Binding affinity and kinetics were measured using biotinylated recombinant human DAAO bound to a Neutravidin surface in a Biacore binding assay. A cu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31148(3-hydroxyquinolin-2(1H)-one, 2 | US9701638, 1)
Affinity DataKd:  13nMAssay Description:Binding affinity and kinetics were measured using biotinylated recombinant human DAAO bound to a Neutravidin surface in a Biacore binding assay. A cu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31147(4H-furo[3,2-b]pyrrole-5-carboxylic acid | CHEMBL49...)
Affinity DataKd:  29nMAssay Description:Binding affinity and kinetics were measured using biotinylated recombinant human DAAO bound to a Neutravidin surface in a Biacore binding assay. A cu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31149(3-hydroxyquinolin-2(1H)-one, 3)
Affinity DataIC50: 3nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31173(naphthyridinone analog., 27)
Affinity DataIC50: 3nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31148(3-hydroxyquinolin-2(1H)-one, 2 | US9701638, 1)
Affinity DataIC50: 4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Rat)
Pfizer

LigandPNGBDBM31173(naphthyridinone analog., 27)
Affinity DataIC50: 4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31156(3-hydroxyquinolin-2(1H)-one, 10)
Affinity DataIC50: 4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31172(3-hydroxyquinolin-2(1H)-one, 26)
Affinity DataIC50: 5nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31161(3-hydroxyquinolin-2(1H)-one, 15)
Affinity DataIC50: 8nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31164(naphthyridinone analog.,18)
Affinity DataIC50: 8nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31152(3-hydroxyquinolin-2(1H)-one, 6)
Affinity DataIC50: 8nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31147(4H-furo[3,2-b]pyrrole-5-carboxylic acid | CHEMBL49...)
Affinity DataIC50: 9nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31151(3-hydroxyquinolin-2(1H)-one, 5)
Affinity DataIC50: 9nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31150(3-hydroxyquinolin-2(1H)-one, 4)
Affinity DataIC50: 10nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31160(3-hydroxyquinolin-2(1H)-one, 14)
Affinity DataIC50: 16nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31165(naphthyridinone analog.,19)
Affinity DataIC50: 32nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31153(3-hydroxyquinolin-2(1H)-one, 7)
Affinity DataIC50: 33nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31157(3-hydroxyquinolin-2(1H)-one, 11)
Affinity DataIC50: 38nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Rat)
Pfizer

LigandPNGBDBM31156(3-hydroxyquinolin-2(1H)-one, 10)
Affinity DataIC50: 40nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Rat)
Pfizer

LigandPNGBDBM31172(3-hydroxyquinolin-2(1H)-one, 26)
Affinity DataIC50: 50nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31154(3-hydroxyquinolin-2(1H)-one, 8)
Affinity DataIC50: 100nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31167(naphthyridinone analog.,21)
Affinity DataIC50: 128nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31155(3-hydroxyquinolin-2(1H)-one, 9)
Affinity DataIC50: 155nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Rat)
Pfizer

LigandPNGBDBM31149(3-hydroxyquinolin-2(1H)-one, 3)
Affinity DataIC50: 180nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Rat)
Pfizer

LigandPNGBDBM31152(3-hydroxyquinolin-2(1H)-one, 6)
Affinity DataIC50: 196nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31158(3-hydroxyquinolin-2(1H)-one, 12)
Affinity DataIC50: 197nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Rat)
Pfizer

LigandPNGBDBM31164(naphthyridinone analog.,18)
Affinity DataIC50: 200nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Rat)
Pfizer

LigandPNGBDBM31148(3-hydroxyquinolin-2(1H)-one, 2 | US9701638, 1)
Affinity DataIC50: 215nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Rat)
Pfizer

LigandPNGBDBM31151(3-hydroxyquinolin-2(1H)-one, 5)
Affinity DataIC50: 308nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Rat)
Pfizer

LigandPNGBDBM31147(4H-furo[3,2-b]pyrrole-5-carboxylic acid | CHEMBL49...)
Affinity DataIC50: 424nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31166(naphthyridinone analog.,20)
Affinity DataIC50: 784nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandPNGBDBM31148(3-hydroxyquinolin-2(1H)-one, 2 | US9701638, 1)
Affinity DataIC50: 855nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Rat)
Pfizer

LigandPNGBDBM31150(3-hydroxyquinolin-2(1H)-one, 4)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31159(3-hydroxyquinolin-2(1H)-one, 13)
Affinity DataIC50: 2.75E+3nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Rat)
Pfizer

LigandPNGBDBM31165(naphthyridinone analog.,19)
Affinity DataIC50: 3.08E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31171(3-hydroxyquinolin-2(1H)-one, 25)
Affinity DataIC50: 3.26E+3nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Rat)
Pfizer

LigandPNGBDBM31161(3-hydroxyquinolin-2(1H)-one, 15)
Affinity DataIC50: 3.67E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandPNGBDBM31149(3-hydroxyquinolin-2(1H)-one, 3)
Affinity DataIC50: 4.62E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandPNGBDBM31164(naphthyridinone analog.,18)
Affinity DataIC50: 7.64E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Rat)
Pfizer

LigandPNGBDBM31160(3-hydroxyquinolin-2(1H)-one, 14)
Affinity DataIC50: 8.47E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Rat)
Pfizer

LigandPNGBDBM31153(3-hydroxyquinolin-2(1H)-one, 7)
Affinity DataIC50: 8.72E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandPNGBDBM31151(3-hydroxyquinolin-2(1H)-one, 5)
Affinity DataIC50: 8.88E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31163(3-hydroxyquinolin-2(1H)-one, 17)
Affinity DataIC50: 1.44E+4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandPNGBDBM31173(naphthyridinone analog., 27)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-amino-acid oxidase(Human)
Pfizer

LigandPNGBDBM31169(3-hydroxyquinolin-2(1H)-one, 23 | US9701638, 14)
Affinity DataIC50: 1.73E+4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
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