Compile Data Set for Download or QSAR
Report error Found 156 Enz. Inhib. hit(s) with all data for entry = 50033467
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345947(3-(4-Chloro-phenyl)-9-prop-2-ynylamino-3H-pyrido[3...)
Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345937(9-(Allyl-methyl-amino)-3-(4-chloro-phenyl)-3H-pyri...)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345948(9-Prop-2-ynylamino-3-p-tolyl-3H-pyrido[3',2':4,5]t...)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345950(3-(4-Bromo-phenyl)-9-prop-2-ynylamino-3H-pyrido[3'...)
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345954(3-(4-Bromo-phenyl)-9-(methyl-prop-2-ynyl-amino)-3H...)
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345931(9-Allylamino-3-(4-methoxy-phenyl)-3H-pyrido[3',2':...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345949(3-(4-Methoxy-phenyl)-9-prop-2-ynylamino-3H-pyrido[...)
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345918(3-(4-Chloro-phenyl)-9-prop-2-ynylamino-3H-thieno[2...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345952(3-(4-Chloro-phenyl)-9-(methyl-prop-2-ynyl-amino)-3...)
Affinity DataIC50: 3.80nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345919(9-Prop-2-ynylamino-3-p-tolyl-3H-thieno[2,3-d:4,5-d...)
Affinity DataIC50: 3.90nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345936(9-Allylamino-3-(4-fluoro-phenyl)-3H-pyrido[3',2':4...)
Affinity DataIC50: 4.40nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345960(9-(2-Methyl-allylamino)-3-phenyl-3H-thieno[2,3-d:4...)
Affinity DataIC50: 4.60nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345935(9-Allylamino-3-(4-fluoro-3-methoxy-phenyl)-3H-pyri...)
Affinity DataIC50: 6.80nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345921(3-(4-Bromo-phenyl)-9-prop-2-ynylamino-3H-thieno[2,...)
Affinity DataIC50: 6.80nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345938(9-(Allyl-methyl-amino)-3-(4-methoxy-phenyl)-3H-pyr...)
Affinity DataIC50: 6.90nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345955(3-(4-Chloro-phenyl)-9-(2-methyl-allylamino)-3H-thi...)
Affinity DataIC50: 7.70nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345923(3-(4-Fluoro-phenyl)-9-prop-2-ynylamino-3H-thieno[2...)
Affinity DataIC50: 8.20nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345966(3-Benzo[b]thiophen-5-yl-9-(2-methyl-allylamino)-3H...)
Affinity DataIC50: 8.90nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50224397(cid_1208332 | CHEMBL428909 | 9-dimethylamino-3-(4-...)
Affinity DataIC50: 9.5nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345957(3-(4-Methoxy-phenyl)-9-(2-methyl-allylamino)-3H-th...)
Affinity DataIC50: 9.60nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345942(3-(4-Methoxy-phenyl)-9-(2-methyl-allylamino)-3H-py...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345953(3-(4-Methoxy-phenyl)-9-(methyl-prop-2-ynyl-amino)-...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345932(9-Allylamino-3-p-tolyl-3H-pyrido[3',2':4,5]thieno[...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345962(3-(4-Fluoro-phenyl)-9-(2-methyl-allylamino)-3H-thi...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345940(3-(4-Chloro-phenyl)-9-(2-methyl-allylamino)-3H-pyr...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345956(9-(2-Methyl-allylamino)-3-p-tolyl-3H-thieno[2,3-d:...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345951(3-(3-Fluoro-4-methoxy-phenyl)-9-prop-2-ynylamino-3...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345934(9-Allylamino-3-(4-bromo-phenyl)-3H-pyrido[3',2':4,...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345920(3-(4-Methoxy-phenyl)-9-prop-2-ynylamino-3H-thieno[...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345958(3-(4-Bromo-phenyl)-9-(2-methyl-allylamino)-3H-thie...)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345941(9-(2-Methyl-allylamino)-3-p-tolyl-3H-pyrido[3',2':...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345964(3-Benzothiazol-5-yl-9-(2-methyl-allylamino)-3H-thi...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345965(3-Benzothiazol-6-yl-9-(2-methyl-allylamino)-3H-thi...)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345929(3-Benzofuran-5-yl-9-prop-2-ynylamino-3H-thieno[2,3...)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345967(3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-9-(2-methyl-...)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345943(3-(4-Bromo-phenyl)-9-(2-methyl-allylamino)-3H-pyri...)
Affinity DataIC50: 43nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345927(3-Benzothiazol-5-yl-9-prop-2-ynylamino-3H-thieno[2...)
Affinity DataIC50: 45nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345963(3-(3-Chloro-phenyl)-9-(2-methyl-allylamino)-3H-thi...)
Affinity DataIC50: 53nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345933(9-Allylamino-3-(4-chloro-phenyl)-3H-pyrido[3',2':4...)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345939(9-(Allyl-methyl-amino)-3-(4-bromo-phenyl)-3H-pyrid...)
Affinity DataIC50: 66nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345959(3-(3-Fluoro-4-methoxy-phenyl)-9-(2-methyl-allylami...)
Affinity DataIC50: 72nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345924(3-(2-Fluoro-4-methoxy-phenyl)-9-prop-2-ynylamino-3...)
Affinity DataIC50: 85nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345944(3-(3-Fluoro-4-methoxy-phenyl)-9-(2-methyl-allylami...)
Affinity DataIC50: 103nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345925(3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-9-prop-2-yny...)
Affinity DataIC50: 106nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345926(3-Benzo[1,3]dioxol-5-yl-9-prop-2-ynylamino-3H-thie...)
Affinity DataIC50: 137nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345969(9-(1,1-Dimethyl-prop-2-ynylamino)-3-p-tolyl-3H-pyr...)
Affinity DataIC50: 171nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345945(3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-9-(2-methyl-...)
Affinity DataIC50: 196nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345928(3-Benzothiazol-6-yl-9-prop-2-ynylamino-3H-thieno[2...)
Affinity DataIC50: 209nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345922(3-(3-Fluoro-4-methoxy-phenyl)-9-prop-2-ynylamino-3...)
Affinity DataIC50: 212nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345930(3-Benzo[b]thiophen-5-yl-9-prop-2-ynylamino-3H-thie...)
Affinity DataIC50: 219nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
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