Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 50028727
Affinity DataIC50: 24nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 430nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 980nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Inhibition of IRAK4More data for this Ligand-Target Pair
Affinity DataKi: 2.90E+3nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
Affinity DataKi: >3.30E+3nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: >3.30E+3nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: >3.30E+3nMAssay Description:Inhibition of Pim1 assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of MAP3K7More data for this Ligand-Target Pair
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair


3D Structure (crystal)





















