Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50028612
TargetProteasome subunit beta type-8(Human)
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277781((2S)-2-[(2S)-2-[(5-ethoxy-1,2-oxazol-3-yl)formamid...)
Affinity DataIC50: 5nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Proteolix

Curated by ChEMBL
LigandPNGBDBM50069989(CHEMBL325041 | (R)-3-methyl-1-((S)-3-phenyl-2-(pyr...)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277889(CHEMBL451887 | CARFILZOMIB)
Affinity DataIC50: 14nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277779(N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)-1-((R)-2-...)
Affinity DataIC50: 21nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277815(3-methoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)...)
Affinity DataIC50: 22nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277816(3-methoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)...)
Affinity DataIC50: 36nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277780(5-ethoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)-...)
Affinity DataIC50: 41nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277818(2-Me-5-thiazole-Ser(OMe)-Ser(OMe)-Phe-ketoepoxide ...)
Affinity DataIC50: 82nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277778(N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)-1-((R)-2-...)
Affinity DataIC50: 93nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277733((2S)-3-methoxy-2-[(2S)-3-methoxy-2-[(5-methyl-1,2-...)
Affinity DataIC50: 238nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277734(N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)-4-methyl-...)
Affinity DataIC50: 607nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277817(N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)-4-methyl-...)
Affinity DataIC50: 784nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed