Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50004504
TargetDNA topoisomerase I(Leishmania donovani)
India Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50239186(CHEBI:50182 | 1,1-Bis(3''-Indolyl)Methane | 3,3''-...)
Affinity DataKd:  5.30E+5nMAssay Description:Binding affinity to recombinant drug-resistant Leishmania donovani LdDR50 topoisomerase 1b large subunit F270L mutant after 24 hrs by equilibrium dia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetDNA topoisomerase type IB small subunit(Leishmania donovani)
India Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50239186(CHEBI:50182 | 1,1-Bis(3''-Indolyl)Methane | 3,3''-...)
Affinity DataKd:  3.80E+5nMAssay Description:Binding affinity to recombinant drug-resistant Leishmania donovani LdDR50 topoisomerase 1b small subunit N184S mutant after 24 hrs by equilibrium dia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
India Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50239186(CHEBI:50182 | 1,1-Bis(3''-Indolyl)Methane | 3,3''-...)
Affinity DataKd:  7.60E+5nMAssay Description:Binding affinity to recombinant drug-resistant Leishmania donovani LdDR50 topoisomerase 1b large subunit F270L, K430N mutant after 24 hrs by equilibr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed