Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50004191
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rat)
Universita Degli Studi Di Bologna

Curated by ChEMBL
LigandPNGBDBM50004704(Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of L-type calcium channel in Wistar rat tail artery smooth muscle cells assessed as blockade of barium-sensitive inward rectifying current...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rat)
Universita Degli Studi Di Bologna

Curated by ChEMBL
LigandPNGBDBM50479921(CHEMBL508166)
Affinity DataIC50: 2.52E+4nMAssay Description:Inhibition of L-type calcium channel in Wistar rat tail artery smooth muscle cells assessed as blockade of barium-sensitive inward rectifying current...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rat)
Universita Degli Studi Di Bologna

Curated by ChEMBL
LigandPNGBDBM50479922(CHEMBL489002)
Affinity DataIC50: 3.34E+4nMAssay Description:Inhibition of L-type calcium channel in Wistar rat tail artery smooth muscle cells assessed as blockade of barium-sensitive inward rectifying current...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rat)
Universita Degli Studi Di Bologna

Curated by ChEMBL
LigandPNGBDBM50004704(Acetic acid 5-(2-dimethylamino-ethyl)-2-(4-methoxy...)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]diltiazem from L-type calcium channel in Sprague-Dawley rat cardiac myocytes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rat)
Universita Degli Studi Di Bologna

Curated by ChEMBL
LigandPNGBDBM50479923(CHEMBL521744)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]diltiazem from L-type calcium channel in Sprague-Dawley rat cardiac myocytes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rat)
Universita Degli Studi Di Bologna

Curated by ChEMBL
LigandPNGBDBM50479922(CHEMBL489002)
Affinity DataKi:  290nMAssay Description:Displacement of [3H]diltiazem from L-type calcium channel in Sprague-Dawley rat cardiac myocytes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rat)
Universita Degli Studi Di Bologna

Curated by ChEMBL
LigandPNGBDBM50479921(CHEMBL508166)
Affinity DataKi:  490nMAssay Description:Displacement of [3H]diltiazem from L-type calcium channel in Sprague-Dawley rat cardiac myocytes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rat)
Universita Degli Studi Di Bologna

Curated by ChEMBL
LigandPNGBDBM50479920(CHEMBL523271)
Affinity DataKi:  2.37E+4nMAssay Description:Displacement of [3H]diltiazem from L-type calcium channel in Sprague-Dawley rat cardiac myocytes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed