Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50030273
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293525(5-methyl-2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293515(2-(4-methylthiazol-2-yl)-N-(pyridin-4-yl)quinazoli...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293527(2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinolin-...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293526(2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)thieno[3,...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293516(2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinazoli...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293520(N-(1H-indazol-5-yl)-2-(6-methylpyridin-2-yl)quinaz...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293519(2-(6-methylpyridin-2-yl)-N-(pyrimidin-4-yl)quinazo...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293514(2-(3-chlorophenyl)-N-(pyridin-4-yl)quinazolin-4-am...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293527(2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinolin-...)
Affinity DataIC50: 58nMAssay Description:Inhibition of TGF-beta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293519(2-(6-methylpyridin-2-yl)-N-(pyrimidin-4-yl)quinazo...)
Affinity DataIC50: 60nMAssay Description:Inhibition of TGF-beta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293526(2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)thieno[3,...)
Affinity DataIC50: 60nMAssay Description:Inhibition of TGF-beta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293520(N-(1H-indazol-5-yl)-2-(6-methylpyridin-2-yl)quinaz...)
Affinity DataIC50: 90nMAssay Description:Inhibition of TGF-beta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293524(6-methyl-2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)...)
Affinity DataIC50: 93nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293516(2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinazoli...)
Affinity DataIC50: 95nMAssay Description:Inhibition of TGF-beta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293513(2-phenyl-N-(pyridin-4-yl)quinazolin-4-amine | CHEM...)
Affinity DataIC50: 194nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293517(2-(6-methylpyridin-2-yl)-N-(2-methylpyridin-4-yl)q...)
Affinity DataIC50: 199nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293518(3-(2-(6-methylpyridin-2-yl)quinazolin-4-ylamino)be...)
Affinity DataIC50: 263nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293525(5-methyl-2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)...)
Affinity DataIC50: 318nMAssay Description:Inhibition of TGF-beta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293515(2-(4-methylthiazol-2-yl)-N-(pyridin-4-yl)quinazoli...)
Affinity DataIC50: 342nMAssay Description:Inhibition of TGF-beta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293518(3-(2-(6-methylpyridin-2-yl)quinazolin-4-ylamino)be...)
Affinity DataIC50: 545nMAssay Description:Inhibition of TGF-beta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293521(N-(1-methyl-1H-indazol-5-yl)-2-(6-methylpyridin-2-...)
Affinity DataIC50: 588nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293522(N-(2-(6-methylpyridin-2-yl)quinazolin-4-yl)benzo[d...)
Affinity DataIC50: 646nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293524(6-methyl-2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)...)
Affinity DataIC50: 745nMAssay Description:Inhibition of TGF-beta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293521(N-(1-methyl-1H-indazol-5-yl)-2-(6-methylpyridin-2-...)
Affinity DataIC50: 794nMAssay Description:Inhibition of TGF-beta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293517(2-(6-methylpyridin-2-yl)-N-(2-methylpyridin-4-yl)q...)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of TGF-beta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293513(2-phenyl-N-(pyridin-4-yl)quinazolin-4-amine | CHEM...)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293514(2-(3-chlorophenyl)-N-(pyridin-4-yl)quinazolin-4-am...)
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of TGF-beta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293513(2-phenyl-N-(pyridin-4-yl)quinazolin-4-amine | CHEM...)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of TGF-beta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293523(N-(1H-benzo[d][1,2,3]triazol-6-yl)-2-(6-methylpyri...)
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293522(N-(2-(6-methylpyridin-2-yl)quinazolin-4-yl)benzo[d...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of TGF-beta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293523(N-(1H-benzo[d][1,2,3]triazol-6-yl)-2-(6-methylpyri...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of TGF-beta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293516(2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinazoli...)
Affinity DataIC50: 6.72E+3nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293517(2-(6-methylpyridin-2-yl)-N-(2-methylpyridin-4-yl)q...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293523(N-(1H-benzo[d][1,2,3]triazol-6-yl)-2-(6-methylpyri...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293522(N-(2-(6-methylpyridin-2-yl)quinazolin-4-yl)benzo[d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293521(N-(1-methyl-1H-indazol-5-yl)-2-(6-methylpyridin-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293520(N-(1H-indazol-5-yl)-2-(6-methylpyridin-2-yl)quinaz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293519(2-(6-methylpyridin-2-yl)-N-(pyrimidin-4-yl)quinazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293518(3-(2-(6-methylpyridin-2-yl)quinazolin-4-ylamino)be...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293515(2-(4-methylthiazol-2-yl)-N-(pyridin-4-yl)quinazoli...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293514(2-(3-chlorophenyl)-N-(pyridin-4-yl)quinazolin-4-am...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed