Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 3097
TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM27950(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Astrazeneca

LigandPNGBDBM27947(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
LigandPNGBDBM27950(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 9nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

LigandPNGBDBM27947(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

LigandPNGBDBM27950(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
LigandPNGBDBM27947(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 19nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

LigandPNGBDBM27949(4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]...)
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

LigandPNGBDBM27951(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

LigandPNGBDBM27952(2-[5-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 69nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

LigandPNGBDBM27953(2-[3-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 120nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Astrazeneca

LigandPNGBDBM27954(3-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]...)
Affinity DataIC50: 250nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Astrazeneca

LigandPNGBDBM27950(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 5.20E+3nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, cholesterol solubilized in Triton WR-1339, and glutathione in a 96-deep well plate. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Astrazeneca

LigandPNGBDBM27947(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 1.20E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, cholesterol solubilized in Triton WR-1339, and glutathione in a 96-deep well plate. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Astrazeneca

LigandPNGBDBM27949(4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]...)
Affinity DataIC50: 1.80E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, cholesterol solubilized in Triton WR-1339, and glutathione in a 96-deep well plate. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Astrazeneca

LigandPNGBDBM27951(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 1.80E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, cholesterol solubilized in Triton WR-1339, and glutathione in a 96-deep well plate. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Astrazeneca

LigandPNGBDBM27952(2-[5-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 2.80E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, cholesterol solubilized in Triton WR-1339, and glutathione in a 96-deep well plate. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Astrazeneca

LigandPNGBDBM27954(3-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]...)
Affinity DataIC50: 2.90E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, cholesterol solubilized in Triton WR-1339, and glutathione in a 96-deep well plate. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
Astrazeneca

LigandPNGBDBM27953(2-[3-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 3.00E+4nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, cholesterol solubilized in Triton WR-1339, and glutathione in a 96-deep well plate. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed